Evidence map›Paper›PMID 28455834›Full record

SynthesisPharmacoEconomics2017

Does the Public Prefer Health Gain for Cancer Patients? A Systematic Review of Public Views on Cancer and its Characteristics.

Liz Morrell, Sarah Wordsworth, Sian Rees, Richard Barker

Abstract readSystematic Review
In one paragraph

Synthesis in PharmacoEconomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Willingness-to-pay for cancer treatment and outcome: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
    Pooled it
  2. Article
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  6. Advanced therapy medicinal products and health technology assessment principles and practices for value-based and sustainable healthcare.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liz MorrellCentre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Room 4403, Level 4, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK. liz.morrell@casmi.org.uk.ORCID http://orcid.org/0000-0001-6382-1795
Sarah WordsworthNuffield Department of Population Health, Health Economics Research Centre, University of Oxford, Oxford, UK.
Sian ReesNuffield Department of Primary Care Health Sciences, Health Experiences Institute, University of Oxford, Oxford, UK.
Richard BarkerCentre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Room 4403, Level 4, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolicies such as the Cancer Drugs Fund in England assumed a societal preference to fund cancer care relative to other conditions, even if that resulted in lower health gain for the population overall.

objectiveThe aim of this study was to investigate the evidence for such a preference among the UK public.

methodsThe MEDLINE, PubMed and Econlit electronic databases were searched for studies relating to preferences for prioritising cancer treatment, as well as studies relating to preferences for the characteristics of cancer (severity of disease, end-of-life). The searches were run in November 2015 and updated in March 2017. Empirical preference studies, studies of public views, and studies in English were included.

resultsWe identified 24 studies relating to cancer preferences. Two directly addressed health trade-offs in the UK-one showed a preference for health gain in cancer, while the other found no such preference but provided results consistent with population health maximisation. Other studies mostly showed support for cancer but did not require a direct health trade-off. Severity and end-of-life searches identified 12 and 6 papers, respectively, which were additional to existing reviews. There is consistent evidence that people give priority to severe illness, while results for end-of-life are mixed.

conclusionWe did not find consistent support for a preference for health gains to cancer patients in the context of health maximisation. The evidence base is small and the results are highly sensitive to study design. There remains a contradiction between these findings and the popular view of cancer, and further work is required to determine the features of cancer which contribute to that view.

Indexed as

Public OpinionAntineoplastic AgentsFinancial ManagementHealth PolicyHumansNeoplasmsResearch DesignSeverity of Illness IndexUnited KingdomAntineoplastic AgentsHealth GainHealth Technology AssessmentIrritable Bowel SyndromePublic PreferenceSocietal Preference

Identifiers

PMID28455834
PMCPMC5548817

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.