Evidence map›Paper›PMID 28455745›Full record

ReviewPediatric nephrology (Berlin, Germany)2018

Expanding the role of vasopressin antagonism in polycystic kidney diseases: From adults to children?

Peter Janssens, Caroline Weydert, Stephanie De Rechter, Karl Martin Wissing, Max Christoph Liebau, Djalila Mekahli

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Diseases of the primary cilia: a clinical characteristics review.Pediatric nephrology (Berlin, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Peter JanssensLaboratory of Pediatrics, University Hospitals Leuven, Leuven, Belgium. peter.janssens@uzbrussel.be.ORCID 0000-0002-0981-8621
Caroline WeydertLaboratory of Pediatrics, University Hospitals Leuven, Leuven, Belgium.
Stephanie De RechterLaboratory of Pediatrics, University Hospitals Leuven, Leuven, Belgium.
Karl Martin WissingDepartment of Nephrology, University Hospitals Brussel, Brussel, Belgium.
Max Christoph LiebauPediatric Nephrology, Department of Pediatrics and Center for Molecular Medicine, University Hospital of Cologne, Cologne, Germany.
Djalila MekahliLaboratory of Pediatrics, University Hospitals Leuven, Leuven, Belgium.
KU Leuven · BECologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEMathys (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic kidney disease (PKD) encompasses a group of genetic disorders that are common causes of renal failure. The two classic forms of PKD are autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney disease (ADPKD). Despite their clinical differences, ARPKD and ADPKD share many similarities. Altered intracellular Ca

Indexed as

AdultAnimalsAntidiuretic Hormone Receptor AntagonistsChildCyclic AMPHumansKidneyPolycystic Kidney, Autosomal DominantSignal TransductionTolvaptanVasopressinsAntidiuretic Hormone Receptor AntagonistsCyclic AMPTolvaptanVasopressinsADPKDARPKDcAMPPolycystic kidney diseaseTolvaptanVasopressin

Identifiers

PMID28455745
OpenAlexW2609432529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.