Evidence map›Paper›PMID 28455608›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2017

Expansion of CD11b

Yuliya V Perfilyeva, Nurshat Abdolla, Yekaterina O Ostapchuk, Raikhan Tleulieva, Vladimir C Krasnoshtanov, Nikolai N Belyaev

Abstract read
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In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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  11. A wrinkle in time: circadian biology in pulmonary vascular health and disease.American journal of physiology. Lung cellular and molecular physiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuliya V PerfilyevaLaboratory of Molecular Immunology and Immunobiotechnology, M. A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan. perfilyevayulya@gmail.com.
Nurshat AbdollaLaboratory of Molecular Immunology and Immunobiotechnology, M. A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
Yekaterina O OstapchukLaboratory of Molecular Immunology and Immunobiotechnology, M. A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
Raikhan TleulievaLaboratory of Molecular Immunology and Immunobiotechnology, M. A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
Vladimir C KrasnoshtanovKazakh Research Institute of Oncology and Radiology, Almaty, Kazakhstan.
Nikolai N BelyaevLaboratory of Molecular Immunology and Immunobiotechnology, M. A. Aitkhozhin's Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
Institute of Plant Biology and Biotechnology · KZAl-Farabi Kazakh National University · KZKazakh Institute of Oncology and Radiology · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMyeloid-derived suppressor cells (MDSCs) are important negative regulators of immune processes in cancer and other pathological conditions. We suggested that MDSCs play a key role in pathogenesis of chronic inflammation, which precedes and, to a certain extent, induces carcinogenesis. The present study aimed at investigation of MDSCs arising during chronic inflammation and light-at-night (LN)-induced stress, which is shown to accelerate chronic diseases. SUBJECTS: 67 CD-1 mice and in vitro MDSC cultures. TREATMENT: Adjuvant arthritis was induced by a subdermal injection of complete Freund's adjuvant. LN was induced by illumination of 750 lx at night.

methodsFlow cytometry for evaluation of cell phenotypes and MTT standard test for cell proliferation were used.

resultsIncreased levels of splenic CD11b

conclusionsOur study raises the possibility that CD11b

Indexed as

AnimalsAntigens, LyArthritis, ExperimentalCD11b AntigenCells, CulturedCircadian RhythmCytokinesIntegrin alpha4LightMaleMiceMyeloid CellsStress, PhysiologicalAntigens, LyCD11b AntigenCytokinesIntegrin alpha4Ly6G antigen, mouseChronic inflammationGranulocytic MDSCLight-at-night-induced stressMonocytic MDSC

Identifiers

PMID28455608
OpenAlexW2609937114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.