Evidence map›Paper›PMID 28455599›Full record

ReviewJournal of anesthesia2017

An update on the management of postoperative nausea and vomiting.

Xuezhao Cao, Paul F White, Hong Ma

3 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of anesthesia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 68 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 4 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04810494 phase4withdrawnnot on this mapstarted 2022, after this paper: background citation

Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting. A Prospective Double Blind Randomized Controlled Study.

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2022 to 2023Enrolled0ConditionsPostoperative Nausea and VomitingArms2% Lidocaine HCl topical solution, 0.9% Sodium chloride
NCT06022705 completednot on this mapstarted 2023, after this paper: background citation

Evaluation of the Effect of APFEL Risk Score and Fasting Periods on Postoperative Nausea and/or Vomiting

Typeobservational_patient_registrySponsorCukurova UniversityRan2023 to 2024Enrolled321ConditionsNausea, Postoperative, Vomiting, Postoperative, APFEL RİSK SCORE
NCT06540885 phase4completednot on this mapstarted 2025, after this paper: background citation

A Comparison Between Palonosetron Versus Granisetron As Postoperative Nausea and Vomiting Prophylaxis In Idiopathic Scoliosis Surgery: A Randomized Control Trial

TypeinterventionalSponsorUniversity of MalayaRan2025 to 2026Enrolled74ConditionsPostoperative Nausea and Vomiting, ScoliosisArmsPalonosetron (Group P), Granisetron (Group G)
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 4 syntheses or guidelines pooled it, 156 citations in OpenAlex.

  1. Pooled it
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  13. Sensory signals for nausea.Trends in neurosciences · 2025
    Review
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  18. Review
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Xuezhao CaoFirst Hospital of China Medical University, Shenyang, China.
Paul F WhiteDepartment of Anesthesiology, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Paul.White@cshs.org.
Hong MaFirst Hospital of China Medical University, Shenyang, China.
Cedars-Sinai Medical Center · USChina Medical University · CNFirst Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative nausea and vomiting (PONV) and postdischarge nausea and vomiting (PDNV) remain common and distressing complications following surgery. PONV and PDNV can delay discharge and recovery and increase medical costs. The high incidence of PONV has persisted in part because of the tremendous growth in ambulatory surgery and the increased emphasis on earlier mobilization and discharge after both minor and major operations. Pharmacological management of PONV should be tailored to the patients' risk level using the PONV and PDNV scoring systems to minimize the potential for these adverse side effects in the postoperative period. A combination of prophylactic antiemetic drugs should be administered to patients with moderate-to-high risk of developing PONV in order to facilitate the recovery process. Optimal management of perioperative pain using opioid-sparing multimodal analgesic techniques and preventing PONV using prophylactic antiemetics are key elements for achieving an enhanced recovery after surgery. Strategies that include reductions of the baseline risk (e.g., adequate hydration, use of opioid-sparing analgesic techniques) as well as a multimodal antiemetic regimen will improve the likelihood of preventing both PONV and PDNV.

Indexed as

Ambulatory Surgical ProceduresAnesthesiaAntiemeticsHumansPostoperative Nausea and VomitingAntiemeticsAntiemetic drugsMultimodal antiemetic therapyNon-pharmacologic antiemetic therapiesPostdischarge nausea and vomitingPostoperative nausea and vomiting

Identifiers

PMID28455599
OpenAlexW2607704845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.