Evidence map›Paper›PMID 28455439›Full record

ArticleCMAJ open2017

Cancer incidence attributable to excess body weight in Alberta in 2012.

Darren R Brenner, Abbey E Poirier, Anne Grundy, Farah Khandwala, Alison McFadden, Christine M Friedenreich

Abstract read
In one paragraph

Article in CMAJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Darren R BrennerAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Abbey E PoirierAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Anne GrundyAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Farah KhandwalaAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Alison McFaddenAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Christine M FriedenreichAffiliations: Department of Cancer Epidemiology and Prevention Research (Brenner, Poirier, Grundy, Khandwala, McFadden, Friedenreich), CancerControl Alberta, Alberta Health Services; Department of Oncology (Brenner, Friedenreich), Cumming School of Medicine; Department of Community Health Sciences (Brenner, Friedenreich), Cumming School of Medicine, University of Calgary, Calgary, Alta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExcess body weight has been consistently associated with colorectal, breast, endometrial, esophageal, gall bladder, pancreatic and kidney cancers. The objective of this analysis was to estimate the proportion of total and site-specific cancers attributable to excess body weight in adults in Alberta in 2012.

methodsWe estimated the proportions of attributable cancers using population attributable risk. Risk estimates were obtained from recent meta-analyses, and exposure prevalence estimates were obtained from the Canadian Community Health Survey. People with a body mass index of 25.00-29.99 kg/m2 and of 30 kg/m2 or more were categorized as overweight and obese, respectively.

resultsAbout 14%-47% of men and 9%-35% of women in Alberta were classified as either overweight or obese; the proportion increased with increasing age for both sexes. We estimate that roughly 17% and 12% of obesity-related cancers among men and women, respectively, could be attributed to excess body weight in Alberta in 2012. The heaviest absolute burden in terms of number of cases was seen for breast cancer among women and for colorectal cancer among men. Overall, about 5% of all cancers in adults in Alberta in 2012 were estimated to be attributable to excess body weight in 2000-2003.

interpretationExcess body weight contributes to a substantial proportion of cases of cancers associated with overweight and obesity annually in Alberta. Strategies to improve energy imbalance and reduce the proportion of obese and overweight Albertans may have a notable impact on cancer incidence in the future.

Identifiers

PMID28455439
PMCPMC5510285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.