Evidence map›Paper›PMID 28455357›Full record

ArticleBiology open2017

Fission yeast neddylation ligase Dcn1 facilitates cohesin cleavage and chromosome segregation at anaphase.

Lan Lin, Li Chen, Phong T Tran

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Lan LinSchool of Medicine, Southeast University, Nanjing, Jiangsu 210009, People's Republic of China.
Li ChenCell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Phong T TranCell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA tranp@mail.med.upenn.edu.ORCID http://orcid.org/0000-0002-2410-2277
Centre National de la Recherche Scientifique · FRSoutheast University · CNUniversity of Pennsylvania · US

Funding

Mechanisms of spindle formationR01GM102215 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI TRAN, PHONG T · 2012 to 2015
$1.3M
NIGMS NIH HHS R01 GM102215
6 · The paper itself

Abstract

Post-translational protein modification such as phosphorylation and ubiquitination are critical during mitosis to ensure proper timing and progression of chromosome segregation. It has been recently recognized that another type of protein modification - neddylation - may also regulate mitosis and chromosome segregation. The conserved protein DCN1 (defective cullin neddylation 1) has been shown, when knocked-down by RNAi, to result in multinucleated cells and/or blockage of cell proliferation. However, how DCN1 functions in mitosis and chromosome segregation is not known. We report here the fission yeast

Indexed as

Chromosome segregationMitosisNeddylation

Identifiers

PMID28455357
PMCPMC5483010
OpenAlexW2608976820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.