Evidence map›Paper›PMID 28455340›Full record

ArticleApplied and environmental microbiology2017

Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis.

Xueying Wang, Yongjin J Zhou, Lei Wang, Wujun Liu, Yuxue Liu, Chang Peng, Zongbao K Zhao

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  9. A de novo peroxidase is also a promiscuous yet stereoselective carbene transferase.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xueying WangDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Yongjin J ZhouDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Lei WangDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Wujun LiuDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Yuxue LiuDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Chang PengDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China.
Zongbao K ZhaoDivision of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, People's Republic of China zhaozb@dicp.ac.cn.
Dalian Institute of Chemical Physics · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NAD and its reduced form NADH function as essential redox cofactors and have major roles in determining cellular metabolic features. NAD can be synthesized through the deamidated and amidated pathways, for which the key reaction involves adenylylation of nicotinic acid mononucleotide (NaMN) and nicotinamide mononucleotide (NMN), respectively. In

Indexed as

Escherichia coliMutationNADNicotinamide MononucleotideNicotinamide-Nucleotide AdenylyltransferaseProtein EngineeringSubstrate SpecificityNADNicotinamide MononucleotideNicotinamide-Nucleotide Adenylyltransferasenicotinate mononucleotidenicotinic acid adenine dinucleotidenicotinic acid mononucleotide adenylyltransferasecofactor engineeringNAD biosynthesisprotein engineering

Identifiers

PMID28455340
PMCPMC5478990
OpenAlexW2609229757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.