ReviewAdvanced drug delivery reviews2017
Biomaterial strategies for generating therapeutic immune responses.
Review in Advanced drug delivery reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 62 citations in OpenAlex.
- Unraveling and Harnessing the Immune Response at the Cell-Biomaterial Interface for Tissue Engineering Purposes.Advanced healthcare materials · 2024Review
- Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Response.Bioengineering (Basel, Switzerland) · 2023Review
- Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy.Journal of nanobiotechnology · 2023Review
- Latest advances on MXenes in biomedical research and health care.MRS bulletin · 2023Review
- Three-dimensional (3D) scaffolds as powerful weapons for tumor immunotherapy.Bioactive materials · 2022Review
- Clickable Biomaterials for Modulating Neuroinflammation.International journal of molecular sciences · 2022Review
- Development of functional nanomedicines for tumor associated macrophages-focused cancer immunotherapy.Theranostics · 2022Review
- Biomaterial and Therapeutic Approaches for the Manipulation of Macrophage Phenotype in Peripheral and Central Nerve Repair.Pharmaceutics · 2021Review
- Endometrial SUSD2Journal of personalized medicine · 2021Review
- Modulating the foreign body response of implants for diabetes treatment.Advanced drug delivery reviews · 2021Review
- Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health.Nature nanotechnology · 2021Review
- Novel function ofIranian journal of basic medical sciences · 2021Article
- Emerging Nano/Micro-Structured Degradable Polymeric Meshes for Pelvic Floor Reconstruction.Nanomaterials (Basel, Switzerland) · 2020Review
- Engineered biomaterials for cancer immunotherapy.MedComm · 2020Review
- Enabling sublingual peptide immunization with molecular self-assemblies.Biomaterials · 2020Article
- Direct Microscopic Observation of Human Neutrophil-Staphylococcus aureus InteractionInfection and immunity · 2019Article
- Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders.Interface focus · 2019Review
- Bioscaffold-Induced Brain Tissue Regeneration.Frontiers in neuroscience · 2019Review
- Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cord.Biomedical materials (Bristol, England) · 2018Article
- Progress Toward the Clinical Translation of Bioinspired Peptide and Protein Assemblies.Advanced healthcare materials · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Biomaterials employed to raise therapeutic immune responses have become a complex and active field. Historically, vaccines have been developed primarily to fight infectious diseases, but recent years have seen the development of immunologically active biomaterials towards an expanding list of non-infectious diseases and conditions including inflammation, autoimmunity, wounds, cancer, and others. This review structures its discussion of these approaches around a progression from single-target strategies to those that engage increasingly complex and multifactorial immune responses. First, the targeting of specific individual cytokines is discussed, both in terms of delivering the cytokines or blocking agents, and in terms of active immunotherapies that raise neutralizing immune responses against such single cytokine targets. Next, non-biological complex drugs such as randomized polyamino acid copolymers are discussed in terms of their ability to raise multiple different therapeutic immune responses, particularly in the context of autoimmunity. Last, biologically derived matrices and materials are discussed in terms of their ability to raise complex immune responses in the context of tissue repair. Collectively, these examples reflect the tremendous diversity of existing approaches and the breadth of opportunities that remain for generating therapeutic immune responses using biomaterials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.