ArticleJournal of biomechanics2017
Evaluation of an aortic valve prosthesis: Fluid-structure interaction or structural simulation?
Article in Journal of biomechanics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Hematologic complications and design challenges in cardiovascular devices.Communications engineering · 2026Review
- Fluid-Structure Interaction Analysis of Human Eye with Descemet Membrane Detachment.Annals of biomedical engineering · 2026Article
- Progressive endothelial coverage enhances hemocompatibility and prevents calcification in bioprosthetic valve tissue.Angiogenesis · 2026Article
- Evaluation of the Haemodynamic Behaviour of Stenosed Aortic Heart Valves Using Fluid Structure Interaction Modelling.International journal for numerical methods in biomedical engineering · 2026Article
- In Silico and In Vitro Comparison of Seven Closed and Semi-Closed Leaflet Designs for Transcatheter Heart Valve Replacements.Bioengineering (Basel, Switzerland) · 2025Article
- Multiscale structure and function of the aortic valve apparatus.Physiological reviews · 2024Review
- Modal Analysis of the Human Brain Using Dynamic Mode Decomposition.Bioengineering (Basel, Switzerland) · 2024Article
- A parametric study regarding structural design of a bioprosthetic aortic valve by 3D fluid-structure interaction simulations.Heliyon · 2024Article
- Shear Stress Quantification in Tissue Engineering Bioreactor Heart Valves: A Computational Approach.Journal of functional biomaterials · 2024Article
- Analysis of the Effect of Thickness on the Performance of Polymeric Heart Valves.Journal of functional biomaterials · 2023Article
- A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement.Scientific reports · 2023Article
- Texas TriValve 1.0 : a reverse‑engineered, open model of the human tricuspid valve.Engineering with computers · 2022Article
- A Single-opening&closing Valve Tester for Direct Measurement of Closing Volume of the Heart Valve.Cardiovascular engineering and technology · 2022Article
- Improving transcatheter aortic valve interventional predictability via fluid-structure interaction modelling using patient-specific anatomy.Royal Society open science · 2022Article
- Precision medicine in human heart modeling : Perspectives, challenges, and opportunities.Biomechanics and modeling in mechanobiology · 2021Review
- Heart Valve Biomechanics: The Frontiers of Modeling Modalities and the Expansive Capabilities ofFrontiers in cardiovascular medicine · 2021Review
- Hemodynamic Modeling of Biological Aortic Valve Replacement Using Preoperative Data Only.Frontiers in cardiovascular medicine · 2020Article
- Article
- Fluid-structure interaction simulation of the brain-skull interface for acute subdural haematoma prediction.Biomechanics and modeling in mechanobiology · 2019Article
- Effect of valve lesion on venous valve cycle: A modified immersed finite element modeling.PloS one · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Bio-inspired polymeric heart valves (PHVs) are excellent candidates to mimic the structural and the fluid dynamic features of the native valve. PHVs can be implanted as prosthetic alternative to currently clinically used mechanical and biological valves or as potential candidate for a minimally invasive treatment, like the transcatheter aortic valve implantation. Nevertheless, PHVs are not currently used for clinical applications due to their lack of reliability. In order to investigate the main features of this new class of prostheses, pulsatile tests in an in-house pulse duplicator were carried out and reproduced in silico with both structural Finite-Element (FE) and Fluid-Structure interaction (FSI) analyses. Valve kinematics and geometric orifice area (GOA) were evaluated to compare the in vitro and the in silico tests. Numerical results showed better similarity with experiments for the FSI than for the FE simulations. The maximum difference between experimental and FSI GOA at maximum opening time was only 5%, as compared to the 46.5% between experimental and structural FE GOA. The stress distribution on the valve leaflets clearly reflected the difference in valve kinematics. Higher stress values were found in the FSI simulations with respect to those obtained in the FE simulation. This study demonstrates that FSI simulations are more appropriate than FE simulations to describe the actual behaviour of PHVs as they can replicate the valve-fluid interaction while providing realistic fluid dynamic results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.