Evidence map›Paper›PMID 28454830›Full record

ArticleAmerican heart journal2017

National patterns in intensity and frequency of outpatient care for apparent treatment-resistant hypertension.

Sreekanth Vemulapalli, Luqin Deng, Manesh R Patel, Meredith L Kilgore, W Schuyler Jones, Lesley H Curtis, Marguerite Ryan Irvin, Laura P Svetkey, Daichi Shimbo, David A Calhoun and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American heart journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sreekanth VemulapalliDuke Clinical Research Institute, Duke University Medical Center, Durham, NC. Electronic address: sreekanth.vemulapalli@duke.edu.
Luqin DengSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL.
Manesh R PatelDuke Clinical Research Institute, Duke University Medical Center, Durham, NC.
Meredith L KilgoreSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL.
W Schuyler JonesDuke Clinical Research Institute, Duke University Medical Center, Durham, NC.
Lesley H CurtisDuke Clinical Research Institute, Duke University Medical Center, Durham, NC.
Marguerite Ryan IrvinSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL.
Laura P SvetkeyDepartment of Medicine, Division of Nephrology, Duke University Medical Center, Durham, NC.
Daichi ShimboDivision of Cardiology, Columbia University, New York, NY.
David A CalhounDivision of Cardiology, University of Alabama at Birmingham, Birmingham, AL.
Paul MuntnerSchool of Public Health, University of Alabama at Birmingham, Birmingham, AL.
University of Alabama at Birmingham · USClinical Research Institute · USDuke Medical Center · USColumbia University · US

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI PATEL, UPTAL D · 2012 to 2016
$5.9M
Cell phone Intervention Trail for Young Adults (CITY)U01HL096720 · NHLBI · DUKE UNIVERSITY · PI SVETKEY, LAURA P · 2009 to 2013
$5.1M
NHLBI NIH HHS U01 HL096720NIDDK NIH HHS P30 DK096493NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

backgroundApparent treatment-resistant hypertension (aTRH) is associated with an increased risk of adverse cardiovascular outcomes. We studied the frequency and intensity of care for aTRH among participants aged 65 years and older in the US-based REGARDS study linked with Medicare claims.

methodsBlood pressure (BP) was measured twice and averaged. aTRH was defined by the use of ≥3 classes of antihypertensive medication and uncontrolled BP (UaTRH, systolic/diastolic BP ≥140/90 mmHg), or ≥4 classes with controlled BP (CaTRH). Participants were categorized as not having aTRH (no aTRH), CaTRH or UaTRH.

resultsAmong 4650 participants with hypertension, 468 (10.1%) had UaTRH, 247 (5.3%) had CaTRH, and 3935 (84.6%) had hypertension but did not have aTRH. For hypertension-related visits, those with UaTRH saw primary care physicians and cardiologists more frequently than those without aTRH (mean primary care visits per year: 2.77 vs 2.27, P<.001; cardiologists: 0.50 vs 0.35, P=.014). Among those with UaTRH, CaTRH, and no aTRH, respectively 73.5%, 68.0%, and 67.5% had >1 hypertension-related visit per year. Among those with UaTRH, males vs females (prevalence ratio=0.78; 95% CI 0.69-0.89), whites vs blacks (0.88; 95% CI 0.78-0.99), and current smokers vs non-smokers (0.66; 95% CI 0.48-0.89) were less likely to receive >1 hypertension-related visit per year. Diagnostic intensity, measured by testing for end organ damage and secondary hypertension, was similar between groups.

conclusionsMany people with UaTRH are not seen more than once per year for hypertension and may benefit from increased care.

Indexed as

AgedAmbulatory CareAntihypertensive AgentsBlood PressureFemaleHumansHypertensionMaleMedicareRetrospective StudiesRisk FactorsTreatment FailureUnited StatesAntihypertensive Agents

Identifiers

PMID28454830
PMCPMC8218938
OpenAlexW2579256408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.