Evidence map›Paper›PMID 28454443›Full record

ArticleOncology letters2017

miR-185-3p regulates the invasion and metastasis of nasopharyngeal carcinoma by targeting WNT2B

Chao Liu, Guo Li, Shuling Ren, Zhongwu Su, Yunyun Wang, Yongquan Tian, Yong Liu, Yuanzheng Qiu

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chao LiuDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Guo LiDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Shuling RenDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Zhongwu SuDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Yunyun WangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Yongquan TianDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Yong LiuDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Yuanzheng QiuDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital Central South University, Changsha, Hunan 410008, P.R. China.
Xiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRs) have been recognised as important regulators of malignant behaviour in different types of human cancer, including nasopharyngeal carcinoma (NPC). A previous study by our group revealed that miR-185-3p regulates the radioresistance of NPC cells. The present study aimed to investigate the effect of miR-185-3p on NPC invasion and metastasis. Human NPC CNE-2 and 5-8F cell lines were transfected with a miR-185-3p mimic and miR-185-3p inhibitor, respectively, and their effects on the invasion and metastasis of these cells was assessed using a wound healing assay and Matrigel invasion assay. The target gene of miR-185-3p, Wnt family member 2B (

Indexed as

metastasismiR-185-3pnasopharyngeal carcinomaWnt family member 2B

Identifiers

PMID28454443
PMCPMC5403522
OpenAlexW2589725668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.