Evidence map›Paper›PMID 28454314›Full record

ArticleOncology letters2017

Synchronous and bilateral oncocytic carcinoma of the breast: A case report and review of the literature.

Hiroko Itagaki, Tomoko Yamamoto, Atsuko Hiroi, Kunio Kawanishi, Eiichiro Noguchi, Tetsuya Ohchi, Takako Kamio, Shingo Kameoka, Hideaki Oda, Yoji Nagashima

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Rare Breast Cancer Subtypes.Current oncology reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hiroko ItagakiDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Tomoko YamamotoDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Atsuko HiroiDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Kunio KawanishiDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Eiichiro NoguchiDepartment of Surgery II, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Tetsuya OhchiDepartment of Surgery II, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Takako KamioDepartment of Surgery II, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Shingo KameokaDepartment of Surgery II, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Hideaki OdaDepartment of Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yoji NagashimaDepartment of Surgical Pathology, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synchronous bilateral breast cancer is rare, and oncocytic carcinoma is an even rarer breast cancer histological subtype. In general, oncocytic tumors are defined as neoplasms with eosinophilic granular cytoplasm and have been reported in various organs. Oncocytic carcinoma of the breast was first documented by Gădăleanu and Craciun in 1987, and 48 cases have since been reported. The present study reports a case of synchronous bilateral breast oncocytic carcinoma. The patient was a 78-year-old woman. Although she exhibited no symptoms, chest computed tomography revealed three multinodular breast tumors: Two in the right breast and one in the left. Core needle biopsy was performed on the three tumors, and the patient was diagnosed with invasive ductal carcinoma with potential apocrine carcinoma. A bilateral modified radical mastectomy was performed. Surgical specimens of the three tumors revealed cord- or nest-forming tumor cells with eosinophilic granular cytoplasm. Immunohistochemically, the tumor cells were markedly positive for mitochondria. Electron microscopy of the tumor samples additionally revealed numerous mitochondria filling the cytoplasm. Based on these findings, the tumors were diagnosed as oncocytic carcinoma. The pathogenesis of oncocytic carcinoma remains to be fully elucidated; thus, additional clinicopathological studies are required.

Indexed as

bilateralbreastmitochondriaoncocytic carcinomasynchronous

Identifiers

PMID28454314
PMCPMC5403532
OpenAlexW2579257734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.