Evidence map›Paper›PMID 28454284›Full record

ArticleOncology letters2017

Anti-apoptotic protein Lifeguard does not act as a tumor marker in breast cancer.

Viktor Maurer, Kerstin Reimers, Hans J Lück, Peter M Vogt, Vesna Bucan

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Viktor MaurerDepartment of Plastic, Hand and Reconstructive Surgery, Hanover Medical School, D-30652 Hanover, Germany.
Kerstin ReimersDepartment of Plastic, Hand and Reconstructive Surgery, Hanover Medical School, D-30652 Hanover, Germany.
Hans J LückGynecologic Oncology Practice, D-30177 Hanover, Germany.
Peter M VogtDepartment of Plastic, Hand and Reconstructive Surgery, Hanover Medical School, D-30652 Hanover, Germany.
Vesna BucanDepartment of Plastic, Hand and Reconstructive Surgery, Hanover Medical School, D-30652 Hanover, Germany.
Medizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to use an enzyme-linked immunosorbent assay (ELISA) to determine the concentrations of Lifeguard (LFG) protein in the serum of 36 patients diagnosed with breast cancer and to compare these values with the concentrations of LFG protein in the serum of 7 healthy volunteers in order to detect a possible association between the expression of LFG in the serum and the degree of malignancy of the disease. Although there is no direct association between the LFG protein concentration in the serum and the degree of malignancy of breast cancer, a statistically significant distribution of the concentration in all investigated samples was observed. This indicated an association between the LFG protein concentration in human serum with a currently unknown factor.

Indexed as

breast cancerLifeguardtumor marker

Identifiers

PMID28454284
PMCPMC5403417
OpenAlexW2580397741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.