Evidence map›Paper›PMID 28454230›Full record

ArticleOncology letters2017

A subpopulation of cancer stem cells identifies radiographic characteristics in glioblastoma.

Ja Eun Kim, Sung Kwon Kim, Jaekyung Shin, Young-Bem Se, Seung Hong Choi, Sung-Hye Park, Seung Ah Choi, Ji Yeoun Lee, Ji Hoon Phi, Kyu-Chang Wang and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. HPVTranslational oncology · 2021
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ja Eun KimDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Sung Kwon KimDepartment of Neurosurgery, Gyeongsang National University School of Medicine, Gyeongsang National University Hospital, Jinju 660-702, Republic of Korea.
Jaekyung ShinDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Young-Bem SeDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Seung Hong ChoiDepartment of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Sung-Hye ParkDepartment of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Seung Ah ChoiDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Ji Yeoun LeeDepartment of Anatomy, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Ji Hoon PhiDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Kyu-Chang WangDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Chul-Kee ParkDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Seung-Ki KimDepartment of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea.
Seoul National University Hospital · KRGyeongsang National University Hospital · KRNew Generation University College · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs), defined by CD133 expression, harbor heterogeneous subpopulations of cells, including endothelial progenitor cells (EPCs). This study aimed to investigate whether a subpopulation of CSCs could affect the radiographic characteristics of glioblastoma. Tissue samples from 10 patients newly diagnosed with glioblastoma were selected according to the radiographic characteristics of their tumors. The patients were divided into two groups based on preoperative magnetic resonance imaging demonstrating contrast enhancement, necrosis and infiltrative patterns: the enhancement/necrosis group (E/N, n=5) and the non-enhancement/infiltration group (NE/I, n=5). Flow cytometry was used to assess the CSCs while immunohistochemistry was used to study microvessel density and the proliferation index. The EPC (CD34

Indexed as

cancer stem cellCD133CD34contrast enhancementendothelial progenitor cellglioblastoma

Identifiers

PMID28454230
PMCPMC5403500
OpenAlexW2565941687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.