Evidence map›Paper›PMID 28453839›Full record

ArticleThe Journal of infectious diseases2017

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Anindya Siddharta, Stephanie Pfaender, Nathalie Jane Vielle, Ronald Dijkman, Martina Friesland, Britta Becker, Jaewon Yang, Michael Engelmann, Daniel Todt, Marc P Windisch and 9 more

Abstract readComparative Study
In one paragraph

Article in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Hand Sanitizers: A Review on Formulation Aspects, Adverse Effects, and Regulations.International journal of environmental research and public health · 2020
    Pooled it
  4. Trial
  5. Hantavirus stability and inactivation.PLoS neglected tropical diseases · 2026
    Article
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  8. Review
  9. Article
  10. Article
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  12. Observational
  13. Article
  14. Review
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anindya SiddhartaInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Stephanie PfaenderDepartment of Infectious diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland.
Nathalie Jane VielleDepartment of Infectious diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland.
Ronald DijkmanDepartment of Infectious diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland.
Martina FrieslandInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Britta BeckerDr Brill + Partner GmbH Institute for Hygiene and Microbiology, Bremen, Germany.
Jaewon YangApplied Molecular Virology, Institut Pasteur Korea, Seongnam, Gyeonggi-do, South Korea.
Michael EngelmannInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Daniel TodtInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Marc P WindischApplied Molecular Virology, Institut Pasteur Korea, Seongnam, Gyeonggi-do, South Korea.
Florian H BrillDr Brill + Partner GmbH Institute for Hygiene and Microbiology, Bremen, Germany.
Joerg SteinmannInstitute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Duisburg, Germany.
Jochen SteinmannDr Brill + Partner GmbH Institute for Hygiene and Microbiology, Bremen, Germany.
Stephan BeckerInstitute for Virology, Philipps University of Marburg, Germany.
Marco P AlvesDepartment of Infectious diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland.
Thomas PietschmannInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Markus EickmannInstitute for Virology, Philipps University of Marburg, Germany.
Volker ThielDepartment of Infectious diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Switzerland.
Eike SteinmannInstitute of Experimental Virology, Twincore, Centre for Experimental and Clinical Infection Research, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.

Indexed as

AntisepsisCoronavirus InfectionsEbolavirusHand HygieneHemorrhagic Fever, EbolaHumansMiddle East Respiratory Syndrome CoronavirusPractice Guidelines as TopicRegression AnalysisRepublic of KoreaSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusVirulenceWorld Health OrganizationZika VirusZika Virus InfectionEbola virusMERSSARSWHOZika virus

Identifiers

PMID28453839
PMCPMC5407053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.