ArticlePloS one2017
FlyLimbTracker: An active contour based approach for leg segment tracking in unmarked, freely behaving Drosophila.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Versatile multiple object tracking in sparse 2D/3D videos via deformable image registration.PLoS computational biology · 2024Article
- Motor dysfunction iniScience · 2022Article
- A fast region-based active contour for non-rigid object tracking and its shape retrieval.PeerJ. Computer science · 2021Article
- Article
- A locomotor assay reveals deficits in heterozygous Parkinson's disease model and proprioceptive mutants in adultProceedings of the National Academy of Sciences of the United States of America · 2019Article
- DeepFly3D, a deep learning-based approach for 3D limb and appendage tracking in tethered, adulteLife · 2019Article
- DeepPoseKit, a software toolkit for fast and robust animal pose estimation using deep learning.eLife · 2019Article
- Using DeepLabCut for 3D markerless pose estimation across species and behaviors.Nature protocols · 2019Article
- Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.PLoS biology · 2019Article
- LimeSeg: a coarse-grained lipid membrane simulation for 3D image segmentation.BMC bioinformatics · 2019Article
- MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology.PloS one · 2019Article
- A Brief History of Simulation Neuroscience.Frontiers in neuroinformatics · 2019Review
- DeepLabCut: markerless pose estimation of user-defined body parts with deep learning.Nature neuroscience · 2018Article
- Article
- GABAergic inhibition of leg motoneurons is required for normal walking behavior in freely movingProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Measuring behavior across scales.BMC biology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Understanding the biological underpinnings of movement and action requires the development of tools for quantitative measurements of animal behavior. Drosophila melanogaster provides an ideal model for developing such tools: the fly has unparalleled genetic accessibility and depends on a relatively compact nervous system to generate sophisticated limbed behaviors including walking, reaching, grooming, courtship, and boxing. Here we describe a method that uses active contours to semi-automatically track body and leg segments from video image sequences of unmarked, freely behaving D. melanogaster. We show that this approach yields a more than 6-fold reduction in user intervention when compared with fully manual annotation and can be used to annotate videos with low spatial or temporal resolution for a variety of locomotor and grooming behaviors. FlyLimbTracker, the software implementation of this method, is open-source and our approach is generalizable. This opens up the possibility of tracking leg movements in other species by modifications of underlying active contour models.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.