ArticlePloS one2017
Potential biological pathways linking Type-D personality and poor health: A cross-sectional investigation.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Personality and Psychoneuroimmunology: A Systems Biology Perspective.Methods in molecular biology (Clifton, N.J.) · 2025Review
- A Controlled Community Study of Distress and Resilience in Women Diagnosed with Fibromyalgia and Systemic Lupus Erythematosus.Journal of clinical psychology in medical settings · 2023Article
- Exploring the Links between Personality and Immune Function.Personality and individual differences · 2022Article
- Type D Personality and Stomatognathic System Disorders in Physiotherapy Students during the COVID-19 Pandemic.Journal of clinical medicine · 2021Article
- The Level of Stress and Coping Strategies in Patients with Multiple Sclerosis and Their Relationships with the Disease Course.Journal of clinical medicine · 2021Article
- Effectiveness and cost effectiveness of a stress management training for leaders of small and medium sized enterprises - study protocol for a randomized controlled-trial.BMC public health · 2021Article
- Competitive Anxiety, and Guilt and Shame Proneness From Perspective Type D and Non-type D Football Players.Frontiers in psychology · 2021Article
- Association between Satisfaction with Life and Personality Types A and D in Young Women with Acne Vulgaris.International journal of environmental research and public health · 2020Article
- A review of psychosocial factors and personality in the treatment of obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2019Review
- Type D Personality as a Risk Factor in Coronary Heart Disease: a Review of Current Evidence.Current cardiology reports · 2018Review
- An exploratory study of adolescent response to fluoxetine using psychological and biological predictors.PeerJ · 2018Article
- Article
- Type D Personality Associated With Increased Risk for Mortality in Adults With Congenital Heart Disease.The Journal of cardiovascular nursingArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType-D personality, defined as a combination of high negative affect and high social isolation, has been associated with poor health outcomes. However, pathways underlying this association are largely unknown. We investigated the relationship between Type-D personality and several biological and behavioral pathways including the autonomic nervous system, the immune system, glucose regulation and sleep in a large, apparently healthy sample.
methodsData from a total of 646 respondents (age 41.6±11.5, 12,2% women) were available for analysis. Persons with Type-D (negative affect and social isolation score ≥10) were contrasted with those without Type-D. Measures of plasma fibrinogen levels, white blood cell count, high sensitivity C-reactive protein, fasting plasma glucose (FPG), cholesterol, high-density and low-density lipoprotein, glycated hemoglobin (HbA1c), creatinine, triglycerides, and albumin were derived from fasting blood samples. Urine norepinephrine and free cortisol were determined by high-performance liquid chromatography. Time-domain heart rate variability (HRV) measures were calculated for the 24hr recording period and for nighttime separately.
resultsPersons with Type-D had higher HbA1c, FPG, and fibrinogen, and lower nighttime HRV than those without Type-D, suggesting worse glycemic control, systemic inflammation and poorer autonomic nervous system modulation in Type-D persons. In addition, those with Type-D reported less social support and greater sleep difficulties while no group differences were observed for alcohol and cigarette consumption, physical activity and body mass index.
conclusionsFindings provide some of the first evidence for multiple possible biological and behavioral pathways between Type-D personality and increased morbidity and mortality.
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