ArticleEye (London, England)2017
Relationship between the optic nerve sheath diameter and lumbar cerebrospinal fluid pressure in patients with normal tension glaucoma.
Article in Eye (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Is Glaucoma a Two-Pressure-Related Optic Neuropathy? A Systematic Review and Meta-Analysis.Turkish journal of ophthalmology · 2024Pooled it
- Optic Nerve Subarachnoid Space Posture Dependency - An MRI Study in Subjects With Normal Tension Glaucoma and Healthy Controls.Investigative ophthalmology & visual science · 2023Trial
- Visual function and cerebrospinal fluid volume along the optic nerve in patients with spontaneous cerebrospinal fluid rhinorrhea: a cross-sectional study.BMC ophthalmology · 2026Article
- Optic nerve sheath diameter measurements monitor the impact of venous sinus stenosis and surgery on intracranial pressure in NF2 meningioma patients.Scientific reports · 2025Article
- Incidence of optic nerve kinking in a cohort of patients with Normal tension glaucoma.Eye (London, England) · 2025Article
- Related studies on measuring the normal values of optic nerve sheath diameter in healthy Chinese adults based on CT scans.Scientific reports · 2025Article
- Effect of Eye Globe and Optic Nerve Morphologies on Gaze-Induced Optic Nerve Head Deformations.Investigative ophthalmology & visual science · 2024Article
- Retrospective longitudinal assessment of optic nerve sheath diameter in patients with malignant glioma.Cancer medicine · 2023Article
- Effects of head-down tilt on optic nerve sheath diameter in healthy subjects.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023Article
- Retinal nerve fiber layer characteristics in patients with spontaneous intracranial hypotension: a retrospective case series.The Journal of international medical research · 2021Observational
- Adduction-Induced Strain on the Optic Nerve in Primary Open Angle Glaucoma at Normal Intraocular Pressure.Current eye research · 2021Article
- Ultra-High Field Magnetic Resonance Imaging of the Retrobulbar Optic Nerve, Subarachnoid Space, and Optic Nerve Sheath in Emmetropic and Myopic Eyes.Translational vision science & technology · 2021Article
- The relation of optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in pediatric neurosurgery practice - Part II: Influence of wakefulness, method of ICP measurement, intra-individual ONSD-ICP correlation and changes after therapy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Three-Decade Evaluation of Cerebrospinal Fluid Pressure in Open-Angle Glaucoma at a Tertiary Care Center.Journal of ophthalmology · 2020Article
- The role of intracranial pressure in glaucoma and therapeutic implications.Eye (London, England) · 2020Review
- Pressure and velocity in intraocular and subarachnoid space fluid chambers: an inseparable couple.Eye (London, England) · 2019Article
- Intracranial and Intraocular Pressure at the Lamina Cribrosa: Gradient Effects.Current neurology and neuroscience reports · 2018Review
- Evaluation of optic nerve subarachnoid space in primary open angle glaucoma using ultrasound examination.PloS one · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PurposeTo investigate on the relationship between the optic nerve sheath diameter (ONSD) and the lumbar cerebrospinal fluid pressure (CSF-p) in Caucasian patients with normal tension glaucoma (NTG).Patients and methodsRetrospective analysis of medical records of patients with open-angle glaucoma in the period from 2005 to 2015 from the Ophthalmology Department, Cantonal Hospital Aarau, Switzerland was performed. A total of 38 patients (mean age 68.6±11.3 years, 21 females and 17 males) fulfilled the diagnostic criteria of NTG and underwent computed tomography (CT) of the orbit and lumbar puncture (LP). In total, 38 age- and gender-matched Caucasian subjects (mean age: 68.9±10.9 years) without known ON diseases served as controls for ONSD measurements. ONSDs were measured at a distance of 3 mm from the posterior globe and lumbar CSF-p was related to the measurements. Statistical analysis was performed by using the independent two-tailed t-test and the non-parametric Spearman's correlation test.ResultsThe mean ONSD in NTGs measured 6.4±0.9 mm and in controls 5.4±0.6 mm. The difference between NTGs and controls showed statistical significance (t-test: P<0.000). The mean CSF-p in NTG was 11.6±3.7 mm Hg. There was no statistical significant correlation between ONSD and CSF-p (Spearman's correlation coefficient ρ=0.06, P=0.72).ConclusionsThis study demonstrates enlarged ONSDs and normal lumbar CSF-p in 38 Caucasian NTG patients. As enlarged ONSDs generally are associated with increased intracranial CSF-p, these results can be explained by a disturbed communication of CSF-p between the intracranial and intraorbital subarachnoid spaces.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.