ReviewInternational journal of molecular sciences2017
Adverse Health Effects of Thirdhand Smoke: From Cell to Animal Models.
Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Serum cotinine cut-points for secondhand smoke exposure assessment in children under 5 years: A systemic review.PloS one · 2022Pooled it
- A Critical Perspective on the Role of Thirdhand Smoke in Tumorigenesis: Initiator or Promoter.Environment & health (Washington, D.C.) · 2026Review
- Memory under siege: the cognitive costs of smoking and vaping.Brain, behavior, & immunity - health · 2025Review
- Article
- Third-hand Smoking Beliefs in Patients with Cancer.Thoracic research and practice · 2025Article
- Third-Hand Smoke Exacerbates HTurkish journal of pharmaceutical sciences · 2024Article
- Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants.Tobacco control · 2024Article
- Clouding Up Cognition? Secondhand Cannabis and Tobacco Exposure Related to Cognitive Functioning in Youth.Biological psychiatry global open science · 2023Article
- Pre- and postnatal exposure to secondhand tobacco smoke and body composition at 12 years: periods of susceptibility.Obesity (Silver Spring, Md.) · 2022Article
- Knowledge and Opinions of Healthcare Professionals about Thirdhand Smoke: A Multi-National, Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2022Article
- Article
- Secondhand tobacco smoke exposure among children under 5 years old: questionnaires versus cotinine biomarkers: a cohort study.BMJ open · 2021Article
- Thirdhand Smoke Contamination and Infant Nicotine Exposure in a Neonatal Intensive Care Unit: An Observational Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Observational
- Beliefs of parents in Kuwait about thirdhand smoke and its relation to home smoking rules: A cross-sectional study.Tobacco induced diseases · 2021Article
- Persistent tobacco smoke residue in multiunit housing: Legacy of permissive indoor smoking policies and challenges in the implementation of smoking bans.Preventive medicine reports · 2020Article
- Thirdhand smoke: Genotoxicity and carcinogenic potential.Chronic diseases and translational medicine · 2020Article
- Smoking and pregnancy: Epigenetics and developmental origins of the metabolic syndrome.Birth defects research · 2019Review
- Medical staff contributions to thirdhand smoke contamination in a neonatal intensive care unit.Tobacco induced diseases · 2019Article
- Knowledge and attitudes toward thirdhand smoke among parents with children under 3 years in Spain.Pediatric research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The newly identified smoke hazard, thirdhand smoke (THS), has gained public attention in recent years but its health impact and biological effects are largely unknown. THS may be defined by "the four Rs": tobacco chemicals that remain, react, re-emit, and/or are resuspended long after active smoking has ceased. This review summarizes recent research progress in the effects of THS on genotoxicity, metabolism and early life development using cellular and animal models. We first reported that THS generated in laboratory systems caused significant DNA damage in human cell lines. Our finding that THS significantly induces oxidative base lesions has been confirmed in skin wounds of mice models exposed to THS. THS also induced metabolomic changes in human reproductive cell lines. Furthermore, we demonstrated that early exposure to THS not only negatively impacts body weight in both male and female mice, but also induces persistent changes to immunological parameters in peripheral blood in these mice. These results indicate that THS is genotoxic at realistic experimental doses and that there may be a window of susceptibility for some forms of cellular damage induced by THS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.