Evidence map›Paper›PMID 28452928›Full record

ReviewInternational journal of molecular sciences2017

Near Infrared Fluorescence Imaging in Nano-Therapeutics and Photo-Thermal Evaluation.

Mukti Vats, Sumit Kumar Mishra, Mahdieh Shojaei Baghini, Deepak S Chauhan, Rohit Srivastava, Abhijit De

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  8. Article
  9. Review
  10. Review
  11. Article
  12. Near-infrared fluorescence imaging in immunotherapy.Advanced drug delivery reviews · 2020
    Review
  13. Article
  14. Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2020
    Review
  15. Safety and efficacy of intravesical chemotherapy and hyperthermia in the bladder: results of a porcine study.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mukti VatsDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 410210, India. muktivatsiitb@gmail.com.
Sumit Kumar MishraMolecular Functional Imaging Laboratory, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Mumbai 410210, India. sumitmishra1089@gmail.com.
Mahdieh Shojaei BaghiniMolecular Functional Imaging Laboratory, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Mumbai 410210, India. mahdieh.shojaei.baghini@gmail.com.
Deepak S ChauhanDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 410210, India. deepakchauhan@iitb.ac.in.
Rohit SrivastavaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 410210, India. rsrivasta@iitb.ac.in.
Abhijit DeMolecular Functional Imaging Laboratory, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Mumbai 410210, India. ade@actrec.gov.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unresolved and paramount challenge in bio-imaging and targeted therapy is to clearly define and demarcate the physical margins of tumor tissue. The ability to outline the healthy vital tissues to be carefully navigated with transection while an intraoperative surgery procedure is performed sets up a necessary and under-researched goal. To achieve the aforementioned objectives, there is a need to optimize design considerations in order to not only obtain an effective imaging agent but to also achieve attributes like favorable water solubility, biocompatibility, high molecular brightness, and a tissue specific targeting approach. The emergence of near infra-red fluorescence (NIRF) light for tissue scale imaging owes to the provision of highly specific images of the target organ. The special characteristics of near infra-red window such as minimal auto-fluorescence, low light scattering, and absorption of biomolecules in tissue converge to form an attractive modality for cancer imaging. Imparting molecular fluorescence as an exogenous contrast agent is the most beneficial attribute of NIRF light as a clinical imaging technology. Additionally, many such agents also display therapeutic potentials as photo-thermal agents, thus meeting the dual purpose of imaging and therapy. Here, we primarily discuss molecular imaging and therapeutic potentials of two such classes of materials, i.e., inorganic NIR dyes and metallic gold nanoparticle based materials.

Indexed as

Spectroscopy, Near-InfraredDrug CarriersFluorescent DyesHumansMetal NanoparticlesNanostructuresNeoplasmsPhotochemotherapyPhototherapyDrug CarriersFluorescent Dyescancergold nanoparticlemolecular imagingNIR fluorescencephotothermal therapy

Identifiers

PMID28452928
PMCPMC5454837

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.