Evidence map›Paper›PMID 28452628›Full record

ReviewClinical gerontologist

Informed Consent to Research with Cognitively Impaired Adults: Transdisciplinary Challenges and Opportunities.

Beth Prusaczyk, Steven M Cherney, Christopher R Carpenter, James M DuBois

Open access · greenAbstract readReview
In one paragraph

Review in Clinical gerontologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 3 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Guideline
  2. A systematic review of interventions for persons living with dementia: The Geriatric ED Guidelines 2.0.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Pooled it
  3. Pooled it
  4. Trial
  5. Emergency Department Visit Outcomes of a Multicenter Randomized Trial of a Fall Prevention Intervention.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Hospitalizations at Home in Israel, a Retrospective Observational Study.Health care analysis : HCA : journal of health philosophy and policy · 2025
    Observational
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Co-designing a web-based intervention (RESTORE) to support self-management of cancer-related fatigue in people living with a brain tumour.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beth Prusaczyka Washington University School of Medicine , St. Louis , Missouri , USA.
Steven M Cherneya Washington University School of Medicine , St. Louis , Missouri , USA.
Christopher R Carpentera Washington University School of Medicine , St. Louis , Missouri , USA.
James M DuBoisa Washington University School of Medicine , St. Louis , Missouri , USA.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
GWB MENTAL HEALTH SERVICE RESEARCH TRAININGT32MH019960 · NIMH · WASHINGTON UNIVERSITY · PI Leopoldo J Cabassa, Byron James Powell · 1995 to 2026
$11.1M
NCATS NIH HHS UL1 TR000448NIMH NIH HHS T32 MH019960
6 · The paper itself

Abstract

Due to issues related to informed research consent, older adults with cognitive impairments are often excluded from high-quality studies that are not directly related to cognitive impairment, which has led to a dearth of evidence for this population. The challenges to including cognitively impaired older adults in research and the implications of their exclusion are a transdisciplinary issue. The ethical challenges and logistical barriers to conducting research with cognitively impaired older adults are addressed from the perspectives of three different fields-social work, emergency medicine, and orthopaedic surgery. Issues related to funding, study design, intervention components, and outcomes are discussed through the unique experiences of three different providers. A fourth perspective-medical research ethics-provides alternatives to exclusion when conducting research with cognitively impaired older adults such as timing, corrective feedback and plain language, and capacity assessment and proxy appointments. Given the increasing aging population and the lack of evidence on cognitively impaired older adults, it is critical that researchers, funders, and institutional review boards not be dissuaded from including this population in research studies.

Indexed as

AgedBiomedical ResearchCognitive DysfunctionEthics Committees, ResearchHumansInformed ConsentPatient SelectionResearch DesignCognitive impairmentethicsinformed consentolder adultstransdisciplinary

Identifiers

PMID28452628
PMCPMC5911394
OpenAlexW2475099978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.