Evidence map›Paper›PMID 28452024›Full record

Article3 Biotech2017

Total phenolics, antioxidant, antitumor, and enzyme inhibitory activity of Indian medicinal and aromatic plants extracted with different extraction methods.

Shivraj Hariram Nile, Arti Shivraj Nile, Young-Soo Keum

Abstract read
In one paragraph

Article in 3 Biotech, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Frequency and spectrum of MFrontiers in plant science · 2022
    Article
  9. Article
  10. Review
  11. Subcritical Water Extraction ofMolecules (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  14. Importance of3 Biotech · 2018
    Review
  15. Article
  16. Bioactive properties of3 Biotech · 2018
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shivraj Hariram NileDepartment of Bio-resources and Food Science, College of Life and Environmental Sciences, Konkuk University, Seoul, 143701, South Korea. nileshivraj@gmail.com.
Arti Shivraj NileDepartment of Bio-resources and Food Science, College of Life and Environmental Sciences, Konkuk University, Seoul, 143701, South Korea.
Young-Soo KeumDepartment of Bio-resources and Food Science, College of Life and Environmental Sciences, Konkuk University, Seoul, 143701, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenolic content, antioxidant, antitumor, and enzyme inhibitory activities of commonly used medicinal herbs from a Unani system of medicine were investigated using four different extraction methods. Among the plants studied, the Hyssopus officinalis L, Origanum vulgare L, and Portulaca oleracea L. extracts showed the highest amount of total phenolics (64.40, 60.35, and 58.81 mg GAE/g) and revealed significant antioxidant activities. The plants also showed a maximum cytotoxic activity as indicated by H. officinalis (82%), O. vulgare (75%), and P. oleracea (72%) showed more than 70% cytotoxicity for breast cancer cells, 82% of the cells were dead at the concentration of 500 mg/mL. The plants H. officinalis, P. oleracea, O. vulgare, and Rubia cordifolia L. revealed more than 80% inhibition towards xanthine oxidase and comprising maximum 70% of inhibition for superoxide dismutase. From results we conclude that there is a strong correlation between phenolic content, antioxidant, and enzyme inhibitory activity among these plants, indicating phenolics are the major compounds for these biological activities. Furthermore, this study provides the basis for the therapeutic importance of studied plants as latent inhibitors of oxidative stress and antitumor cell proliferation which correlate with the ethnobotanical data contained in the Unani system of medicine.

Indexed as

AntioxidantAntitumorTotal phenolicsUnani medicineXanthine oxidase

Identifiers

PMID28452024
PMCPMC5428111

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.