Evidence map›Paper›PMID 28451995›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

A Protocol to Prepare Decellularized Stem Cell Matrix for Rejuvenation of Cell Expansion and Cartilage Regeneration.

Jingting Li, Ming Pei

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  11. Articular Cartilage Regeneration in Veterinary Medicine.Advances in experimental medicine and biology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Site-Dependent Lineage Preference of Adipose Stem Cells.Frontiers in cell and developmental biology · 2020
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jingting LiStem Cell and Tissue Engineering Laboratory, Department of Orthopaedics, Division of Exercise Physiology, and Mechanical and Aerospace Engineering, West Virginia University, Morgantown, WV, USA.
Ming PeiStem Cell and Tissue Engineering Laboratory, Department of Orthopaedics, West Virginia University, PO Box 9196, One Medical Center Drive, Morgantown, WV, 26506-9196, USA. mpei@hsc.wvu.edu.
West Virginia University · US

Funding

Decellularized Matrix and Cartilage RegenerationR01AR067747 · NIAMS · WEST VIRGINIA UNIVERSITY · PI PEI, MING · 2016 to 2020
$1.7M
Decellularized Stem Cell Matrix Rejuvenates Human Cells from Herniated DiscsR03AR062763 · NIAMS · WEST VIRGINIA UNIVERSITY · PI PEI, MING · 2013 to 2015
$222k
NIAMS NIH HHS R01 AR067747NIAMS NIH HHS R03 AR062763
6 · The paper itself

Abstract

Traditional ex vivo expansion of adult stem cells yields an insufficient quantity of less potent cells. Here we describe the fabrication of decellularized matrix deposited by synovium-derived stem cells (SDSCs). This matrix could serve as a three-dimensional expansion system to rejuvenate cells for proliferation and tissue-specific differentiation potential, which could benefit cartilage regeneration. The decellularized stem cell matrix (DSCM) might be a powerful system for tissue engineering and regeneration.

Indexed as

ChondrogenesisAdult Stem CellsCartilageCell DifferentiationCell ProliferationCells, CulturedExtracellular MatrixHumansRegenerationRejuvenationSynovial MembraneTissue EngineeringTissue ScaffoldsCartilage regenerationCartilage tissue engineeringCell expansionChondrogenesisDecellularized stem cell matrixSynovium-derived stem cells

Identifiers

PMID28451995
PMCPMC7261600
OpenAlexW2610119907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.