Evidence map›Paper›PMID 28451766›Full record

ArticleTechniques in coloproctology2017

Sacral neurostimulation for low anterior resection syndrome after radical resection for rectal cancer: evaluation of treatment with the LARS score.

M D'Hondt, F Nuytens, L Kinget, M Decaestecker, B Borgers, I Parmentier

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Low Anterior Resection Syndrome Evaluation and Management.Clinics in colon and rectal surgery · 2026
    Review
  5. Observational
  6. Article
  7. Article
  8. Review
  9. Optimising functional outcomes in rectal cancer surgery.Langenbeck's archives of surgery · 2021
    Review
  10. Article
  11. Overlooked Long-Term Complications of Colorectal Surgery.Clinics in colon and rectal surgery · 2019
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

M D'HondtDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, President Kennedylaan 4, 8500, Kortrijk, Belgium. mathieudhondt2000@yahoo.com.
F NuytensDepartment of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, President Kennedylaan 4, 8500, Kortrijk, Belgium.
L KingetFaculty of Medicine, KU Leuven, Leuven, Belgium.
M DecaesteckerFaculty of Medicine, KU Leuven, Leuven, Belgium.
B BorgersFaculty of Medicine and Health Sciences, UGent, De Pintelaan 135, 9000, Ghent, Belgium.
I ParmentierDepartment of Oncology and Statistics, Groeninge Hospital, President Kennedylaan 4, 8500, Kortrijk, Belgium.
AZ Groeninge · BEKU Leuven · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSacral neurostimulation (SNS) has proven to be an effective treatment modality for low anterior resection syndrome (LARS). The primary aim of this study is to investigate the impact of SNS on all symptoms of LARS, not merely on fecal incontinence. Furthermore, we wanted to evaluate whether the LARS score could be useful as a tool to evaluate SNS treatment.

methodsAll patients diagnosed with minor or major LARS, unresponsive to conservative therapy for fecal incontinence, who underwent sacral neuromodulation for LARS at Groeninge Hospital, Kortrijk, Belgium, were prospectively enrolled in the study. The primary endpoint was the reduction in the severity of LARS. This was assessed by validated questionnaires: the LARS score and the Wexner score.

resultsEleven patients underwent definite implantation of the SNS device. All patients showed a substantial decrease in their Wexner scores: The mean score was reduced from 17.7 to 4.6 (Z: 2.93; p: 0.0033). Additionally, the mean LARS score dropped from 36.9 to 11.4 (Z: 2.93; p: 0.0033). Furthermore, there was a significant amelioration of all symptoms of LARS.

conclusionsOur study shows that SNS is effective for all symptoms of LARS. The authors believe that in patients who receive SNS for LARS, it could be useful to determine the LARS score to evaluate the complexity of the symptoms and their response to treatment.

Indexed as

Severity of Illness IndexAdultAgedAged, 80 and overDigestive System Surgical ProceduresElectric Stimulation TherapyFecal IncontinenceFemaleHumansImplantable NeurostimulatorsIntestinal DiseasesMaleMiddle AgedPostoperative ComplicationsProspective StudiesRectal NeoplasmsFecal incontinenceLARSLow anterior resection syndromeRectal cancerSacral neurostimulation

Identifiers

PMID28451766
OpenAlexW2609533195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.