Evidence map›Paper›PMID 28451760›Full record

ArticleJournal of mathematical biology2017

Reconstruction of LGT networks from tri-LGT-nets.

Gabriel Cardona, Joan Carles Pons

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Article in Journal of mathematical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gabriel CardonaDepartment of Mathematics and Computer Science, University of the Balearic Islands, 07122, Palma, Spain. gabriel.cardona@uib.es.ORCID 0000-0001-8845-4290
Joan Carles PonsDepartment of Mathematics and Computer Science, University of the Balearic Islands, 07122, Palma, Spain.ORCID 0000-0002-0313-3357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phylogenetic networks have gained attention from the scientific community due to the evidence of the existence of evolutionary events that cannot be represented using trees. A variant of phylogenetic networks, called LGT networks, models specifically lateral gene transfer events, which cannot be properly represented with generic phylogenetic networks. In this paper we treat the problem of the reconstruction of LGT networks from substructures induced by three leaves, which we call tri-LGT-nets. We first restrict ourselves to a class of LGT networks that are both mathematically treatable and biologically significant, called BAN-LGT networks. Then, we study the decomposition of such networks in subnetworks with three leaves and ask whether or not this decomposition determines the network. The answer to this question is negative, but if we further impose time-consistency (species involved in a later gene transfer must coexist) the answer is affirmative, up to some redundancy that can never be recovered but is fully characterized.

Indexed as

Gene Transfer, HorizontalModels, GeneticPhylogenyComputer SimulationEvolution, MolecularGene Regulatory NetworksMathematical ConceptsLateral gene transfersPhylogenetic networksTriplets

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What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.