Trial reportEuropean journal of applied physiology2017
Effects of 4 weeks of low-load unilateral resistance training, with and without blood flow restriction, on strength, thickness, V wave, and H reflex of the soleus muscle in men.
Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Comparing adaptations from blood flow restriction exercise training using regulated or unregulated pressure systems: A systematic review and meta-analysis.Clinical rehabilitation · 2024Pooled it
- A Systematic Review and Meta-Analysis on Neural Adaptations Following Blood Flow Restriction Training: What We Know and What We Don't Know.Frontiers in physiology · 2020Pooled it
- Submaximal low-load resistance exercise with blood flow restriction produces similar results to low-load exercise to failure for muscle size and strength, but not endurance.European journal of applied physiology · 2026Trial
- Effects of Low-Load Blood-Flow Restriction Training Versus High-Load Resistance Training on Neuromuscular Performance and Neuromuscular Activation.Scandinavian journal of medicine & science in sports · 2026Trial
- Comparable muscle fatigue responses across different low-load blood flow restriction protocols among women.European journal of applied physiology · 2025Trial
- Concurrent training effects on H reflex, V wave and contractile properties of the plantar flexors: insights into different resistance training types.European journal of applied physiology · 2025Trial
- Contralateral training effects of low-intensity blood-flow restricted and high-intensity unilateral resistance training.European journal of applied physiology · 2021Trial
- Patterns of responses and time-course of changes in muscle size and strength during low-load blood flow restriction resistance training in women.European journal of applied physiology · 2021Trial
- Nerve conduction during acute blood-flow restriction with and without low-intensity exercise Nerve conduction and blood-flow restriction.Scientific reports · 2020Trial
- Low-load blood flow restriction elicits greater concentric strength than non-blood flow restriction resistance training but similar isometric strength and muscle size.European journal of applied physiology · 2020Trial
- Peer-reviewed by human experts: AI failed in key steps to generate a scoping review on the neural mechanisms of cross-education.European journal of applied physiology · 2026Article
- The effect of blood flow restriction combined with neuromuscular electrical stimulation on knee joint function: A systematic review and meta-analysis.Journal of orthopaedics · 2025Review
- Blood flow restriction augments the cross-education effect of isometric handgrip training.European journal of applied physiology · 2024Article
- The effect of blood flow restriction training combined with electrical muscle stimulation on neuromuscular adaptation: a randomized controlled trial.Frontiers in physiology · 2023Article
- Greater neuromuscular fatigue following low-load blood flow restriction than non-blood flow restriction resistance exercise among recreationally active men.Journal of neurophysiology · 2022Article
- Unilateral, bilateral, and alternating muscle actions elicit similar muscular responses during low load blood flow restriction exercise.European journal of applied physiology · 2021Article
- Does partial activation of the neuromuscular system induce cross-education training effect? Case of a pilot study on motor imagery and neuromuscular electrical stimulation.European journal of applied physiology · 2021Article
- Neuromuscular Adaptations after an Altitude Training Camp in Elite Judo Athletes.International journal of environmental research and public health · 2021Article
- The cross education of strength and skill following unilateral strength training in the upper and lower limbs.Journal of neurophysiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo test the effects of 4 weeks of unilateral low-load resistance training (LLRT), with and without blood flow restriction (BFR), on maximal voluntary contraction (MVC), muscle thickness, volitional wave (V wave), and Hoffmann reflex (H reflex) of the soleus muscle.
methodsTwenty-two males were randomly distributed into three groups: a control group (CTR; n = 8); a low-load blood flow restriction resistance training group (BFR-LLRT; n = 7), who were an inflatable cuff to occlude blood flow; and a low-load resistance training group without blood flow restriction (LLRT; n = 7). The training consisted of four sets of unilateral isometric LLRT (25% of MVC) three times a week over 4 weeks.
resultsMVC increased 33% (P < 0.001) and 22% (P < 0.01) in the trained leg of both BFR-LLRT and LLRT groups, respectively. The soleus thickness increased 9.5% (P < 0.001) and 6.5% (P < 0.01) in the trained leg of both BFR-LLRT and LLRT groups, respectively. However, neither MVC nor thickness changed in either of the legs tested in the CTR group (MVC -1 and -5%, and muscle thickness 1.9 and 1.2%, for the control and trained leg, respectively). Moreover, V wave and H reflex did not change significantly in all the groups studied (V
conclusionsCollectively, the present data suggest that in spite of the changes occurring in soleus strength and thickness, 4 weeks of low-load resistance training, with or without BFR, does not cause any change in neural drive or motoneuronal excitability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.