Evidence map›Paper›PMID 28451521›Full record

ArticleFrontiers in cellular and infection microbiology2017

T3SS-Independent Uptake of the Short-Trip Toxin-Related Recombinant NleC Effector of Enteropathogenic

Anne-Sophie Stolle, Stefanie Norkowski, Britta Körner, Jürgen Schmitz, Lena Lüken, Maj Frankenberg, Christian Rüter, M Alexander Schmidt

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Speaking the host language: howMicrobiology (Reading, England) · 2023
    Review
  4. Review
  5. How Do Biomolecules Cross the Cell Membrane?Accounts of chemical research · 2022
    Article
  6. Article
  7. The T3SS Effector Protease NleC Is Active withinPathogens (Basel, Switzerland) · 2021
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anne-Sophie StolleInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Stefanie NorkowskiInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Britta KörnerInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Jürgen SchmitzInstitute of Experimental Pathology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Lena LükenInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Maj FrankenbergInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
Christian RüterInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
M Alexander SchmidtInstitute of Infectiology, Center for Molecular Biology of Inflammation, University of MünsterMünster, Germany.
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effector proteins secreted by the type 3 secretion system (T3SS) of pathogenic bacteria have been shown to precisely modulate important signaling cascades of the host for the benefit of the pathogens. Among others, the non-LEE encoded T3SS effector protein NleC of enteropathogenic

Indexed as

Recombinant ProteinsAmino Acid SequenceAnimalsBacterial ToxinsEndocytosisEnteropathogenic Escherichia coliEscherichia coli ProteinsHeLa CellsHost-Pathogen InteractionsHumansHydrogen-Ion ConcentrationInterleukin-1betaLysosomesNF-kappa BPhotobacteriumProtein DomainsBacterial ToxinsEscherichia coli ProteinsInterleukin-1betaNF-kappa BRecombinant ProteinsRELA protein, humanTranscription Factor RelAType III Secretion SystemsZ0986 protein, E coliA-B toxinsendocytosisendosomal escapeEPECNF-κB signalingNleCT3SS effectors

Identifiers

PMID28451521
PMCPMC5390045
OpenAlexW2606579599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.