Evidence map›Paper›PMID 28451516›Full record

ArticleGMS hygiene and infection control2017

Antibiotic resistance: What is so special about multidrug-resistant Gram-negative bacteria?

Martin Exner, Sanjay Bhattacharya, Bärbel Christiansen, Jürgen Gebel, Peter Goroncy-Bermes, Philippe Hartemann, Peter Heeg, Carola Ilschner, Axel Kramer, Elaine Larson and 8 more

Open access · greenAbstract read
In one paragraph

Article in GMS hygiene and infection control, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 196 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
196citing papers in PubMed, 3 pooled it
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

196 citing papers in PubMed, 3 syntheses or guidelines pooled it, 433 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Prevalence and Genomic Characterization of ESBL-ProducingAntibiotics (Basel, Switzerland) · 2026
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136 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 5 countries.

Martin ExnerInstitute of Hygiene and Public Health, Bonn University, Bonn, Germany.
Sanjay BhattacharyaTata Medical Center, Kolkata, India.
Bärbel ChristiansenDepartment of Internal Hygiene, Schleswig-Holstein University Hospital, Kiel, Germany.
Jürgen GebelInstitute of Hygiene and Public Health, Bonn University, Bonn, Germany.
Peter Goroncy-BermesSchülke & Mayr GmbH, Norderstedt, Germany.
Philippe HartemannDepartement Environnement et Santé Publique S.E.R.E.S., Faculté de Médecine, Nancy, France.
Peter HeegInstitute of Medical Microbiology and Hygiene, University of Tübingen, Germany.
Carola IlschnerInstitute of Hygiene and Public Health, Bonn University, Bonn, Germany.
Axel KramerInstitute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany.
Elaine LarsonSchool of Nursing, Columbia University, New York, USA.
Wolfgang MerkensSchülke & Mayr GmbH, Norderstedt, Germany.
Martin MielkeRobert Koch Institute (RKI), Berlin, Germany.
Peter OltmannsSchülke & Mayr GmbH, Norderstedt, Germany.
Birgit RossHospital Hygiene, Essen University Hospital, Essen, Germany.
Manfred RotterHygiene Institute, Medical University Vienna, Austria.
Ricarda Maria SchmithausenInstitute of Hygiene and Public Health, Bonn University, Bonn, Germany.
Hans-Günther SonntagInstitute of Hygiene and Medical Microbiology, University of Heidelberg, Germany.
Matthias TrautmannDepartment of Hospital Hygiene, Stuttgart Hospital, Stuttgart, Germany.
University of Bonn · DEInstitute of Medical Microbiology and Hygiene · DEColumbia University · USEssen University Hospital · DEKlinikum Stuttgart · DEMedical University of Vienna · ATRobert Koch Institute · DESanté Publique France · FRTata Medical Center · INUniversitätsmedizin Greifswald · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past years infections caused by multidrug-resistant Gram-negative bacteria have dramatically increased in all parts of the world. This consensus paper is based on presentations, subsequent discussions and an appraisal of current literature by a panel of international experts invited by the Rudolf Schülke Stiftung, Hamburg. It deals with the epidemiology and the inherent properties of Gram-negative bacteria, elucidating the patterns of the spread of antibiotic resistance, highlighting reservoirs as well as transmission pathways and risk factors for infection, mortality, treatment and prevention options as well as the consequences of their prevalence in livestock. Following a global, One Health approach and based on the evaluation of the existing knowledge about these pathogens, this paper gives recommendations for prevention and infection control measures as well as proposals for various target groups to tackle the threats posed by Gram-negative bacteria and prevent the spread and emergence of new antibiotic resistances.

Indexed as

agriculturebiocidesdisinfectionepidemiologyinfection control measuresmultidrug-resistant Gram-negative bacteriareservoirsresistance patternssurveillancetherapy

Identifiers

PMID28451516
PMCPMC5388835
OpenAlexW2618798650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.