ReviewGlobal spine journal2017
Spinal Compression Fracture Management: A Review of Current Treatment Strategies and Possible Future Avenues.
Review in Global spine journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Re-evaluating vertebral height restoration assessment in osteoporotic compression fractures: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Development and validation of a clinical risk stratification model for lumbar vertebral compression fractures in patients with lumbar disc herniation.Bone reports · 2026Article
- A 3D-printed hybrid vertebroplasty, kyphoplasty and screw augmentation teaching model simulating high and low bone mineral densities.Brain & spine · 2026Article
- The kiva system versus balloon kyphoplasty for vertebral compression fracture: a meta-analysis of randomized control trials.North American Spine Society journal · 2025Review
- Virtual Reality-Based Therapy Improves Balance, Quality of Life, and Mitigates Pain and Fear of Falling in Women with Bone Mineral Density Loss: A Meta-Analysis of Randomized Controlled Trials.Life (Basel, Switzerland) · 2025Review
- Predictors of Vertebroplasty Selection in Older Adults with Osteoporotic Vertebral Compression Fractures: A Real-World Cohort Study.Clinical interventions in aging · 2025Article
- Percutaneous Vertebroplasty and Balloon Kyphoplasty for Painful Osteoporotic Vertebral Compression Fractures: A Health Technology Assessment.Ontario health technology assessment series · 2025Article
- Percutaneous endoscopic treatment for osteoporotic vertebral compression fracture complicated with lumbar spinal stenosis: a case report and literature review.Frontiers in medicine · 2025Article
- Low-energy vertebral fractures requiring a fusion in the elderly associate higher mortality than high-energy injuries.Brain & spine · 2025Article
- Personalized Approaches to Spine Surgery.International journal of spine surgery · 2024Article
- Spinal orthoses in osteoporotic vertebral fractures of the elderly.Journal of spine surgery (Hong Kong) · 2023Article
- Review
- Retrospective Review of 181 Patients with Pathologic Vertebral Compression Fractures.Journal of the Pediatric Orthopaedic Society of North America · 2023Article
- A narrative review of the pharmaceutical management of osteoporosis.Annals of joint · 2023Review
- Management of Osteoporotic Vertebral Fracture: Review Update 2022.Asian spine journal · 2022Article
- Managements of osteoporotic vertebral compression fractures: A narrative review.World journal of orthopedics · 2022Review
- The Role of Spinal Orthoses in Osteoporotic Vertebral Fractures of the Elderly Population (Age 60 Years or Older): Systematic Review.Global spine journal · 2021Article
- Analysis on the Effect of Different Surgical Methods on the Treatment of Senile Osteoporotic Spinal Compression Fractures and the Influencing Factors of Complications.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Spinal Dorsal Rami Injection and Radiofrequency Neurolysis for Low Back Pain Caused by Osteoporosis-Induced Thoracolumbar Vertebral Compression Fractures.Journal of rehabilitation medicine. Clinical communications · 2021Article
- Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study.Frontiers in medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designNarrative review.
objectiveDespite the numerous treatment options for vertebral compression fractures, a consensus opinion for the management of patients with these factures has not been established. This review is meant to provide an up-to-date overview of the most common treatment strategies for compression fractures and to suggest possible routes for the development of clearer treatment guidelines.
methodsA comprehensive database search of PubMed was performed. All results from the past 30 years were obtained and evaluated based on title and abstract. The full length of relevant studies was analyzed for level of evidence, and the strongest studies were used in this review.
resultsThe major treatment strategies for patients with compression fractures are conservative pain management and vertebral augmentation. Despite potential adverse effects, medical management, including nonsteroidal anti-inflammatory drugs, calcitonin, teriparatide, and bisphosphonates, remains the first-line therapy for patients. Evidence suggests that vertebral augmentation, especially some of the newer procedures, have the potential to dramatically reduce pain and improve quality of life. At this time, balloon-assisted kyphoplasty is the procedure with the most evidence of support.
conclusionsBased on current literature, it is evident that there is a lack of standard of care for patients with vertebral compression fractures, which is either due to lack of evidence that a procedure is successful or due to serious adverse effects encountered with prolonged treatment. For a consensus to be reached, prospective clinical trials need to be formulated with potential new biomarkers to assess efficacy of treatment strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.