ArticleJournal of virology1988
DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation.
Article in Journal of virology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding.Molecular cancer · 2008Article
- v-Myb represses the transcription of Ets-2.Oncogene · 2007Article
- Functional analysis of carboxy-terminal deletion mutants of c-Myb.Journal of virology · 1999Article
- Transformation by v-Myb.Oncogene · 1999Review
- Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo.Molecular and cellular biology · 1993Article
- Individual repeats of Drosophila Myb can function in transformation by v-Myb.Journal of virology · 1993Article
- Transformation by v-myb correlates with trans-activation of gene expression.Molecular and cellular biology · 1990Article
- trans activation of gene expression by v-myb.Molecular and cellular biology · 1990Article
- Characterization of the sequence-specific interaction of mouse c-myb protein with DNA.The EMBO journal · 1990Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The product of the v-myb oncogene of avian myeloblastosis virus is a nuclear protein with an associated DNA-binding activity. We demonstrated that the highly conserved amino-terminal domain of p48v-myb is required for its associated DNA-binding activity. This activity is not required for the nuclear localization of p48v-myb. Furthermore, the associated DNA-binding activity and nuclear localization of p48v-myb together are not sufficient for transformation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.