ReviewInternational journal of retina and vitreous2017
Macular edema is a rare finding in untreated vitreoretinal lymphoma: small case series and review of the literature.
Review in International journal of retina and vitreous, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Multimodal imaging for diagnosis and follow-up of primary vitreoretinal lymphoma: A systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Ocular Imaging in Intraocular Lymphoma: A Review.Clinical & experimental ophthalmology · 2026Review
- Multimodal imaging characteristics in eyes with vitreoretinal lymphoma treated with intravitreal rituximab.International ophthalmology · 2021Observational
- Cystoid Macular Oedema as a Presenting Feature of Vitreoretinal Lymphoma.Ocular oncology and pathology · 2020Article
- Incidence, Prevalence, and Ocular Comorbidities of Primary Vitreoretinal Lymphoma in the TriNetX Global Collaborative Network.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine the occurrence of macular edema (ME) in vitreoretinal lymphoma (VRL).
methodsRetrospective analysis of 17 patients (31 eyes) with VRL. A review of the literature was done as well.
resultsNine patients (15 eyes) had fluorescein angiography and/or optical coherence tomography at presentation. In the ME group (six eyes of four patients), three patients (five eyes) had prior chemotherapy and radiation. Excluding eyes with radiation retinopathy (three eyes), rate of ME was 25% (3/12). When two unirradiated fellow eyes of eyes with radiation retinopathy were also excluded, ME rate was 10% (1/10). Excluding the eyes with intraocular surgery, the rate of ME was 0%. In the group without ME (nine eyes of six patients), one patient (one eye) was treated with chemotherapy and radiation and three patients (five eyes) with chemotherapy. Review of the literature showed that the ME was found between 2 and 60% of cases, but most of the cases with ME had prior interventions.
conclusionsMacular edema in VRL is not uncommon but usually related to prior interventions. Macular edema as an initial presentation of VRL is rare.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.