Evidence map›Paper›PMID 28451383›Full record

ArticleBiomedical reports2017

Animal models of atherosclerosis.

Yee Ting Lee, Victoria Laxton, Hiu Yu Lin, Yin Wah Fiona Chan, Sophia Fitzgerald-Smith, Tsz Ling Olivia To, Bryan P Yan, Tong Liu, Gary Tse

Abstract read
In one paragraph

Article in Biomedical reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Preclinical models of atherosclerosis: An overview.Iranian journal of basic medical sciences · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Tackling Atherosclerosis via Selected Nutrition.International journal of molecular sciences · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. Survey of Approaches for Investigation of Atherosclerosis In Vivo.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  17. Construction of point mutation rabbits using CRISPR/Cas9.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2021
    Article
  18. Article
  19. Recent Application of Zebrafish Models in Atherosclerosis Research.Frontiers in cell and developmental biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yee Ting LeeSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR, P.R. China.
Victoria LaxtonIntensive Care Department, Royal Brompton and Harefield NHS Trust, London SW3 6NP, UK.
Hiu Yu LinSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, SAR, P.R. China.
Yin Wah Fiona ChanSchool of Biological Sciences, University of Cambridge, Cambridge CB2 1AG, UK.
Sophia Fitzgerald-SmithFaculty of Medicine, University of Bristol, Bristol BS8 1TH, UK.
Tsz Ling Olivia ToDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, P.R. China.
Bryan P YanDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, P.R. China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin 300211, P.R. China.
Gary TseDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a significant cause of morbidity and mortality globally. Many animal models have been developed to study atherosclerosis, and permit experimental conditions, diet and environmental risk factors to be carefully controlled. Pathophysiological changes can be produced using genetic or pharmacological means to study the harmful consequences of different interventions. Experiments using such models have elucidated its molecular and pathophysiological mechanisms, and provided platforms for pharmacological development. Different models have their own advantages and disadvantages, and can be used to answer different research questions. In the present review article, different species of atherosclerosis models are outlined, with discussions on the practicality of their use for experimentation.

Indexed as

animal modelsatherosclerosisporcineprimaterabbit

Identifiers

PMID28451383
PMCPMC5403338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.