Evidence map›Paper›PMID 28451356›Full record

ArticleChemical science2017

Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1,4-addition/Michael reaction through dynamic kinetic resolution under iminium catalysis. Development and mechanistic insights.

Ane Orue, Uxue Uria, David Roca-López, Ignacio Delso, Efraím Reyes, Luisa Carrillo, Pedro Merino, Jose L Vicario

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ane OrueDepartment of Organic Chemistry II , University of the Basque Country (UPV/EHU) , P.O. Box 644 , 48080 Bilbao , Spain.
Uxue UriaDepartment of Organic Chemistry II , University of the Basque Country (UPV/EHU) , P.O. Box 644 , 48080 Bilbao , Spain.
David Roca-LópezDepartamento de Síntesis y Estructura de Biomoléculas , Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) , Universidad de Zaragoza , CSIC , Spain.
Ignacio DelsoServicio de Resonancia Magnética Nuclear , Centro de Química y Materiales de Aragón (CEQMA) , Universidad de Zaragoza , CSIC , Spain.
Efraím ReyesDepartment of Organic Chemistry II , University of the Basque Country (UPV/EHU) , P.O. Box 644 , 48080 Bilbao , Spain.
Luisa CarrilloDepartment of Organic Chemistry II , University of the Basque Country (UPV/EHU) , P.O. Box 644 , 48080 Bilbao , Spain.ORCID 0000-0001-5208-6780
Pedro MerinoDepartamento de Síntesis y Estructura de Biomoléculas , Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) , Universidad de Zaragoza , CSIC , Spain.
Jose L VicarioDepartment of Organic Chemistry II , University of the Basque Country (UPV/EHU) , P.O. Box 644 , 48080 Bilbao , Spain.ORCID 0000-0001-6557-1777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-Hydroxydihydropyran-5-ones behave as excellent polyfunctional reagents able to react with enals through oxa-Michael/Michael process cascade under the combination of iminium and enamine catalysis. These racemic hemiacetalic compounds are used as unconventional

Identifiers

PMID28451356
PMCPMC5376714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.