Evidence map›Paper›PMID 28451317›Full record

ArticleChemical science2017

A resorcinarene for inhibition of Aβ fibrillation.

Xu Han, Jiyong Park, Wei Wu, Andres Malagon, Lingyu Wang, Edgar Vargas, Athula Wikramanayake, K N Houk, Roger M Leblanc

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Xu HanDepartment of Chemistry , Cox Science Center , University of Miami , Coral Gables , Florida 33146 , USA . Email: rml@miami.edu.
Jiyong ParkDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , USA . Email: houk@chem.ucla.edu.ORCID 0000-0002-3225-4510
Wei WuDepartment of Biology , Cox Science Center , University of Miami , Coral Gables , Florida 33146 , USA.
Andres MalagonDepartamento de Quimica , Universidad de los Andes , Cr. 1 No. 18A 10 , Bogota 111711 , Colombia.
Lingyu WangDepartment of Biology , Cox Science Center , University of Miami , Coral Gables , Florida 33146 , USA.
Edgar VargasDepartamento de Quimica , Universidad de los Andes , Cr. 1 No. 18A 10 , Bogota 111711 , Colombia.
Athula WikramanayakeDepartment of Biology , Cox Science Center , University of Miami , Coral Gables , Florida 33146 , USA.
K N HoukDepartment of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , USA . Email: houk@chem.ucla.edu.
Roger M LeblancDepartment of Chemistry , Cox Science Center , University of Miami , Coral Gables , Florida 33146 , USA . Email: rml@miami.edu.
University of Miami · USUniversidad de Los Andes · COUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid-β peptides (Aβ) fibrillation is the hallmark of Alzheimer's disease (AD). However, it has been challenging to discover potent agents in order to inhibit Aβ fibrillation. Herein, we demonstrated the effect of resorcinarene on inhibiting Aβ fibrillation

Identifiers

PMID28451317
PMCPMC5398272
OpenAlexW2556622111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.