Evidence map›Paper›PMID 28451314›Full record

ArticleChemical science2017

Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters.

Nicholas J Race, Adele Faulkner, Gabriele Fumagalli, Takayuki Yamauchi, James S Scott, Marie Rydén-Landergren, Hazel A Sparkes, John F Bower

Abstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Enantioselective Borylcupration/Cyclization of Alkene-Tethered Oxime Esters.Angewandte Chemie (International ed. in English) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Synthesis of Indolines and Derivatives by Aza-Heck Cyclization.Angewandte Chemie (International ed. in English) · 2019
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Diethylzinc-Mediated Metalloamination-Alkylation ofSynlett : accounts and rapid communications in synthetic organic chemistry · 2018
    Article
  18. Heck-like Reactions Involving Heteroatomic Electrophiles.European journal of organic chemistry · 2017
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicholas J RaceSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.
Adele FaulknerSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.
Gabriele FumagalliSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.ORCID 0000-0003-2454-8591
Takayuki YamauchiSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.
James S ScottAstraZeneca , Alderley Park , Macclesfield , Cheshire SK10 4TG , UK.
Marie Rydén-LandergrenAstraZeneca , Pepparedsleden 1 , Mölndal , 43183 , Sweden.
Hazel A SparkesSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.
John F BowerSchool of Chemistry , University of Bristol , Bristol , BS8 1TS , UK . Email: john.bower@bris.ac.uk.

Funding

European Research Council 639594
6 · The paper itself

Abstract

The first examples of highly enantioselective Narasaka-Heck cyclizations are described. A SPINOL-derived P,N-ligand system enables Pd-catalyzed 5-

Identifiers

PMID28451314
PMCPMC5390761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.