Evidence map›Paper›PMID 28451305›Full record

ArticleChemical science2017

Responsive hetero-organelle partition conferred fluorogenic sensing of mitochondrial depolarization.

Zhongwei Xue, Hu Zhao, Jian Liu, Jiahuai Han, Shoufa Han

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhongwei XueState Key Laboratory for Physical Chemistry of Solid Surfaces , Department of Chemical Biology , College of Chemistry and Chemical Engineering , The Key Laboratory for Chemical Biology of Fujian Province , The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation , Innovation Center for Cell Signalling Network , Xiamen University , Xiamen , 361005 , China . Email: shoufa@xmu.edu.cn ; Tel: +86-0592-2181728.
Hu ZhaoState Key Laboratory for Physical Chemistry of Solid Surfaces , Department of Chemical Biology , College of Chemistry and Chemical Engineering , The Key Laboratory for Chemical Biology of Fujian Province , The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation , Innovation Center for Cell Signalling Network , Xiamen University , Xiamen , 361005 , China . Email: shoufa@xmu.edu.cn ; Tel: +86-0592-2181728.
Jian LiuState Key Laboratory for Physical Chemistry of Solid Surfaces , Department of Chemical Biology , College of Chemistry and Chemical Engineering , The Key Laboratory for Chemical Biology of Fujian Province , The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation , Innovation Center for Cell Signalling Network , Xiamen University , Xiamen , 361005 , China . Email: shoufa@xmu.edu.cn ; Tel: +86-0592-2181728.
Jiahuai HanState Key Laboratory of Cellular Stress Biology , Innovation Center for Cell Signalling Network , School of Life Sciences , Xiamen University , Xiamen , 361005 , China.
Shoufa HanState Key Laboratory for Physical Chemistry of Solid Surfaces , Department of Chemical Biology , College of Chemistry and Chemical Engineering , The Key Laboratory for Chemical Biology of Fujian Province , The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation , Innovation Center for Cell Signalling Network , Xiamen University , Xiamen , 361005 , China . Email: shoufa@xmu.edu.cn ; Tel: +86-0592-2181728.
Xiamen University · CNXiamen University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malfunctioning organelles are often difficult to probe with classical organelle-homing sensors owing to disruption of physiological organelle-probe affinity. We herein report the use of a responsive hetero-organelle partition and signal activable probe (RC-TPP) for detecting mitochondrial depolarization, a pathologically relevant event featuring loss of the electrical potentials across the mitochondrial membrane (Δ

Identifiers

PMID28451305
PMCPMC5364656
OpenAlexW2553259603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.