Evidence map›Paper›PMID 28451278›Full record

ArticleChemical science2017

Magnetic circular dichroism studies of iron(ii) binding to human calprotectin.

Tessa M Baker, Toshiki G Nakashige, Elizabeth M Nolan, Michael L Neidig

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Spectroscopic and computational investigations of Cobalt(II) binding to the innate immune protein human calprotectin.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Iron Acquisition by Bacterial Pathogens: Beyond Tris-Catecholate Complexes.Chembiochem : a European journal of chemical biology · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Human calprotectin affects the redox speciation of iron.Metallomics : integrated biometal science · 2017
    Article
  18. Nickel Sequestration by the Host-Defense Protein Human Calprotectin.Journal of the American Chemical Society · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tessa M BakerDepartment of Chemistry , University of Rochester , Rochester , New York 14627 , USA . Email: neidig@chem.rochester.edu.
Toshiki G NakashigeDepartment of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , USA . Email: lnolan@mit.edu.
Elizabeth M NolanDepartment of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , USA . Email: lnolan@mit.edu.
Michael L NeidigDepartment of Chemistry , University of Rochester , Rochester , New York 14627 , USA . Email: neidig@chem.rochester.edu.
Massachusetts Institute of Technology · USUniversity of Rochester · US

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
NIEHS NIH HHS P30 ES002109
6 · The paper itself

Abstract

Calprotectin (CP) is an abundant metal-chelating protein involved in host defense, and the ability of human CP to bind Fe(ii) in a calcium-dependent manner was recently discovered. In the present study, near-infrared magnetic circular dichroism spectroscopy is employed to investigate the nature of Fe(ii) coordination at the two transition-metal-binding sites of CP that are a His

Identifiers

PMID28451278
PMCPMC5361872
OpenAlexW2530393641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.