ArticleChemical science2017
Fluorinative ring-opening of cyclopropanes by hypervalent iodine reagents. An efficient method for 1,3-oxyfluorination and 1,3-difluorination.
Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 121 citations in OpenAlex.
- Programmable divergent electrochemical ring-opening multifunctionalization of strained rings.Nature chemistry · 2026Article
- Article
- Strain-Release-Driven Electrochemical Skeletal Rearrangement of Non-Biased Alkyl Cyclopropanes/Butanes.Angewandte Chemie (International ed. in English) · 2025Article
- Recent Progress in Synthetic Applications of Hypervalent Iodine(III) Reagents.Chemical reviews · 2024Review
- Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes.Angewandte Chemie (International ed. in English) · 2023Article
- Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis ofACS catalysis · 2022Article
- A copper-catalyzed four-component reaction of arylcyclopropanes, nitriles, carboxylic acids andChemical science · 2022Article
- Substrate-controlled C-H or C-C alkynylation of cyclopropanes: generation of aryl radical cations by direct light activation of hypervalent iodine reagents.Chemical science · 2022Article
- Catalytic alkene skeletal modification for the construction of fluorinated tertiary stereocenters.Chemical science · 2022Article
- Cooperative NHC/Photoredox Catalyzed Ring-Opening of Aryl Cyclopropanes to 1-Aroyloxylated-3-Acylated Alkanes.Angewandte Chemie (International ed. in English) · 2021Article
- Expanding organofluorine chemical space: the design of chiral fluorinated isosteres enabled by I(i)/I(iii) catalysis.Chemical science · 2021Review
- Electrochemical C-C bond cleavage of cyclopropanes towards the synthesis of 1,3-difunctionalized molecules.Nature communications · 2021Article
- Ring-opening 1,3-arylboration of arylcyclopropanes mediated by BClRSC advances · 2020Article
- Boron tribromide as a reagent for anti-Markovnikov addition of HBr to cyclopropanes.Chemical science · 2020Article
- Electrochemical Vicinal Difluorination of Alkenes: Scalable and Amenable to Electron-Rich Substrates.Angewandte Chemie (International ed. in English) · 2020Article
- A new hypervalent iodine(iii/v) oxidant and its application to the synthesis of 2Chemical science · 2019Article
- An umpolung strategy to react catalytic enols with nucleophiles.Nature communications · 2019Article
- Photoredox-catalyzed oxo-amination of aryl cyclopropanes.Nature communications · 2019Article
- Rh(III)-Catalyzed Cyclopropanation of Unactivated Olefins Initiated by C-H Activation.Synlett : accounts and rapid communications in synthetic organic chemistry · 2019Article
- Trifluoromethylthiolation-arylation of diazocarbonyl compounds by modified Hooz multicomponent coupling.Chemical science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new method is presented for 1,3-difluorination and 1,3-oxyfluorination reactions. The process is based on iodonium mediated opening of 1,1-disubstituted cyclopropanes. The reaction proceeds with high chemo- and regioselectivity under mild reaction conditions typically at room temperature in a couple of hours. The reaction probably occurs
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.