Evidence map›Paper›PMID 28451184›Full record

ArticleChemical science2017

Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity.

Nichola A Smith, Pingyu Zhang, Simon E Greenough, Michael D Horbury, Guy J Clarkson, Daniel McFeely, Abraha Habtemariam, Luca Salassa, Vasilios G Stavros, Christopher G Dowson and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ru(II) Complex Grafted TiNanomaterials (Basel, Switzerland) · 2023
    Article
  5. Metals to combat antimicrobial resistance.Nature reviews. Chemistry · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Potential therapeutic approaches for a sleeping pathogen: tuberculosis a case for bioinorganic chemistry.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Review
  16. Enhancing the Activity of Drugs by Conjugation to Organometallic Fragments.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Review
  17. Article
  18. An unusual bidentate methionine ruthenium(II) complex: photo-uncaging and antimicrobial activity.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  19. Metal Complexes, an Untapped Source of Antibiotic Potential?Antibiotics (Basel, Switzerland) · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Nichola A SmithDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Pingyu ZhangDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Simon E GreenoughDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Michael D HorburyDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Guy J ClarksonDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Daniel McFeelySchool of Life Sciences , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: C.G.Dowson@warwick.ac.uk.
Abraha HabtemariamDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Luca SalassaCIC biomaGUNE , Paseo de Miramón 182 , Donostia-San Sebastián , 20009 , Spain.
Vasilios G StavrosDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.
Christopher G DowsonSchool of Life Sciences , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: C.G.Dowson@warwick.ac.uk.ORCID 0000-0002-8294-8836
Peter J SadlerDepartment of Chemistry , University of Warwick , Gibbet Hill Road , Coventry CV4 7AL , UK . Email: P.J.Sadler@warwick.ac.uk.ORCID 0000-0001-9160-1941
University of Warwick · GBIkerbasque · ES

Funding

European Research Council 247450Medical Research Council G0701062Medical Research Council MR/N002679/1
6 · The paper itself

Abstract

The novel photoactive ruthenium(ii) complex

Identifiers

PMID28451184
PMCPMC5365061
OpenAlexW2511874499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.