Evidence map›Paper›PMID 28450955›Full record

ArticleExperimental and therapeutic medicine2017

α- and β-Naphthoflavone synergistically attenuate H

Yong Zhu, Fangfang Bi, Yanchun Li, Huiming Yin, Na Deng, Haiquan Pan, Dongfang Li, Bo Xiao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yong ZhuDepartment of Neurology, The First Affiliated Hospital of Hunan University of Medicine, Huaihua, Hunan 418000, P.R. China.
Fangfang BiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Yanchun LiDepartment of Neurology, The First Affiliated Hospital of Hunan University of Medicine, Huaihua, Hunan 418000, P.R. China.
Huiming YinDepartment of Respiration, The First Affiliated Hospital of Hunan University of Medicine, Huaihua, Hunan 418000, P.R. China.
Na DengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Haiquan PanDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Dongfang LiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Bo XiaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.
Hunan University · CNXiangya Hospital Central South University · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated an association between neurological diseases and oxidative stress (OS). Naphthoflavone is a synthetic derivative of naturally occurring flavonoids that serves an important role in the treatment and prevention of OS-related diseases. The current study was designed to apply α- and β-Naphthoflavone individually and in combination to counteract the detrimental effects of OS on neurons

Indexed as

antioxidant enzyme activityoxidative stressp38 mitogen-activated protein kinaseα-Naphthoflavoneβ-Naphthoflavone

Identifiers

PMID28450955
PMCPMC5403206
OpenAlexW2578128645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.