Evidence map›Paper›PMID 28450782›Full record

ArticleInternational journal of nanomedicine2017

Gold nanorod-based poly(lactic-co-glycolic acid) with manganese dioxide core-shell structured multifunctional nanoplatform for cancer theranostic applications.

Lei Wang, Dong Li, Yongwei Hao, Mengya Niu, Yujie Hu, Hongjuan Zhao, Junbiao Chang, Zhenzhong Zhang, Yun Zhang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  12. PLGA-Based Composites for Various Biomedical Applications.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Lei WangSchool of Pharmaceutical Sciences, Zhengzhou University.
Dong LiSchool of Pharmaceutical Sciences, Zhengzhou University.
Yongwei HaoSchool of Pharmaceutical Sciences, Zhengzhou University.
Mengya NiuSchool of Pharmaceutical Sciences, Zhengzhou University.
Yujie HuSchool of Pharmaceutical Sciences, Zhengzhou University.
Hongjuan ZhaoSchool of Pharmaceutical Sciences, Zhengzhou University.
Junbiao ChangKey Laboratory of Targeting Therapy and Diagnosis for Critical Disease, Henan Province.
Zhenzhong ZhangSchool of Pharmaceutical Sciences, Zhengzhou University.
Yun ZhangSchool of Pharmaceutical Sciences, Zhengzhou University.
Target (United States) · USZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, photothermal therapy has become a promising strategy in tumor treatment. However, the therapeutic effect was seriously hampered by the low tissue penetration of laser. Therefore, in this study, radiofrequency (RF) with better tissue penetration was used for tumor hyperthermia. First, one type of gold nanorods (AuNRs) suitable for RF hyperthermia was selected. Then, poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with AuNRs and docetaxel (DTX) (PLGA/AuNR/DTX) NPs were constructed. Finally, manganese dioxide (MnO

Indexed as

AnimalsDelayed-Action PreparationsDocetaxelDrug Delivery SystemsFemaleGoldHumansHyperthermia, InducedLactic AcidMagnetic Resonance ImagingManganese CompoundsMCF-7 CellsMiceNanoparticlesNanoshellsNanotubesDelayed-Action PreparationsDocetaxelGoldLactic AcidManganese Compoundsmanganese dioxideOxidesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerTaxoidscontrolled releasedual-mode imaginggold nanorodhyperthermiamanganese dioxidepoly(lactic-co-glycolic acid)radiofrequency

Identifiers

PMID28450782
PMCPMC5399988
OpenAlexW2606180408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.