Evidence map›Paper›PMID 28450781›Full record

ArticleInternational journal of nanomedicine2017

Simple and effective label-free electrochemical immunoassay for carbohydrate antigen 19-9 based on polythionine-Au composites as enhanced sensing signals for detecting different clinical samples.

Zhengjun Huang, Zhouqian Jiang, Chengfei Zhao, Wendi Han, Liqing Lin, Ailin Liu, Shaohuang Weng, Xinhua Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 56 citations in OpenAlex.

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  10. Tailor-Made Nanomaterials for Diagnosis and Therapy of Pancreatic Ductal Adenocarcinoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhengjun HuangDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Zhouqian JiangDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Chengfei ZhaoDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Wendi HanDepartment of Pharmacy, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Liqing LinDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Ailin LiuDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Shaohuang WengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Xinhua LinDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbohydrate antigen 19-9 (CA19-9) is an important biomarker for the early diagnosis and clinical monitoring of pancreatic cancer. Reliable, simple, and accurate methods for the detection of CA19-9 are still urgently needed. In this study, polythionine-Au composites (AuNPs@ PThi) were designed and prepared through one-pot reaction using HAuCl

Indexed as

Biomarkers, TumorBiosensing TechniquesCA-19-9 AntigenCase-Control StudiesElectrochemical TechniquesElectrodesGoldHumansImmunoassayLimit of DetectionNanoparticlesPancreatic NeoplasmsReproducibility of ResultsSensitivity and SpecificitySignal-To-Noise RatioBiomarkers, TumorCA-19-9 AntigenGoldcarbohydrate antigen 19-9clinical samplelabel-free electrochemical immunoassaypolythionine-Au compositessignal amplification

Identifiers

PMID28450781
PMCPMC5399979
OpenAlexW2607447456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.