ArticleEthiopian journal of health sciences2016
Status of Serum and Salivary Levels of Superoxide Dismutase in Type 2 Diabetes Mellitus with Oral Manifestations: A Case Control Study.
Article in Ethiopian journal of health sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Within-Subject Reliability and between-Subject Variability of Oxidative Stress Markers in Saliva of Healthy Subjects: A Longitudinal Pilot Study.Disease markers · 2017Trial
- Beneficial Effects of Grape Pomace Extract on Hyperglycemia, Dyslipidemia, and Oxidative Stress in Experimental Diabetes Mellitus.Molecules (Basel, Switzerland) · 2025Article
- Role of oxidative stress in prediabetes development.Biochemistry and biophysics reports · 2025Review
- Myoinositol improves sperm parameters in diabetic rats by reducing oxidative stress and regulating apoptosis-related genes.Journal of molecular histology · 2025Article
- Clinical Response Characteristics of Salivary Proteins in the Management Strategy of Diabetes-Associated Periodontitis.Journal of proteome research · 2025Article
- The Other Side of the Perfect Cup: Coffee-Derived Non-Polyphenols and Their Roles in Mitigating Factors Affecting the Pathogenesis of Type 2 Diabetes.International journal of molecular sciences · 2024Review
- Sesamin: A Promising Therapeutic Agent for Ameliorating Symptoms of Diabetes.Molecules (Basel, Switzerland) · 2023Article
- Correlation of glycemic control with salivary oxidative markers in subjects with prediabetes and diabetes: A cross-sectional study.Journal of diabetes and metabolic disorders · 2023Article
- Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants.Antioxidants (Basel, Switzerland) · 2022Review
- Melatonin protects against nonylphenol caused pancreatic β-cells damage through MDM2-P53-P21 axis.Toxicology research · 2022Article
- Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women.International journal of dentistry · 2020Article
- Effect of Storage Time and Temperature on Salivary Total Antioxidant Capacity, Total Oxidant Status, and Oxidant Stress Index.Acta stomatologica Croatica · 2019Article
- Effect of glycemic control and disease duration on cardiac autonomic function and oxidative stress in type 2 diabetes mellitus.Journal of diabetes and metabolic disorders · 2018Article
- Serum Extracellular Superoxide Dismutase Is Associated with Diabetic Retinopathy Stage in Chinese Patients with Type 2 Diabetes Mellitus.Disease markers · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType 2 Diabetes Mellitus is a very well known metabolic disorder that has reached epidemic proportions worldwide. Evidence suggests that oxidative stress increases in Diabetes Mellitus because of the excessive production of reactive oxygen species and an impaired antioxidant defence mechanism. This study estimated, compared and correlated the serum and salivary Superoxide dismutase levels in healthy subjects and subjects with Type 2 Diabetes Mellitus having oral manifestations. MATERIALS AND
methodsIn this study, serum and salivary Superoxide dismutase levels were estimated in 45 healthy subjects and 45 patients with Type 2 Diabetes Mellitus with oral manifestations.
resultsThe mean serum and salivary Superoxide dismutase levels were significantly decreased in subjects with Type 2 Diabetes Mellitus with oral manifestations compared to the healthy subjects. Positive correlation in both healthy and diabetics was observed between serum and salivary samples.
conclusionThis study highlights that the abnormally high levels of oxidative stress in diabetics coupled with simultaneous decline in antioxidant defence mechanism results in complications in Diabetes mellitus. Thus exploring saliva for antioxidant markers that accurately reflect the redox status of the body is worthwhile.
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