ArticleScientific reports2017
Multi-functional Ultrasonic Micro-elastography Imaging System.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Miniaturized dual-element transducer-based intravascular ultrasonic elastography: a preliminaryQuantitative imaging in medicine and surgery · 2026Article
- Nondestructive Mechanical Characterization of Bioengineered Tissues by Digital Holography.ACS biomaterials science & engineering · 2025Article
- Multi-parametric Photoacoustic Imaging Combined with Acoustic Radiation Force Impulse Imaging for Applications in Tissue Engineering.Annals of biomedical engineering · 2025Article
- Four-Dimensional (4D) Ultrasound Shear Wave Elastography Using Sequential Excitation.IEEE transactions on bio-medical engineering · 2025Article
- A lightweight multi scale fusion network for IGBT ultrasonic tomography image segmentation.Scientific reports · 2025Article
- Compound Acoustic Radiation Force Impulse Imaging of Bovine Eye by Using Phase-Inverted Ultrasound Transducer.Sensors (Basel, Switzerland) · 2024Article
- Quantitative Optical Coherence Elastography of the Optic Nerve Head In Vivo.IEEE transactions on bio-medical engineering · 2024Article
- Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine.Oncogene · 2023Review
- Nanobomb optical coherence elastography in multilayered phantoms.Biomedical optics express · 2023Article
- Local elasticity evaluation of acid-denatured collagen by photoacoustic spectroscopy.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023Article
- Simultaneous Assessment of the Whole Eye Biomechanics Using Ultrasonic Elastography.IEEE transactions on bio-medical engineering · 2023Article
- Endocrine Tumor Classification via Machine-Learning-Based Elastography: A Systematic Scoping Review.Cancers · 2023Article
- Three-dimensional mechanical characterization of murine skeletal muscle using quantitative micro-elastography.Biomedical optics express · 2022Article
- High-Frequency Ultrasound Elastography to Assess the Nonlinear Elastic Properties of the Cornea and Ciliary Body.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Non-contact elastography methods in mechanobiology: a point of view.European biophysics journal : EBJ · 2022Review
- Development of Moderate Intensity Focused Ultrasound (MIFU) for Ocular Drug Delivery.BME frontiers · 2022Article
- 2-D Ultrasonic Array-Based Optical Coherence Elastography.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- High resolution optical coherence elastography of retina under prosthetic electrode.Quantitative imaging in medicine and surgery · 2021Article
- Ultrasonic elastography to assess biomechanical properties of the optic nerve head and peripapillary sclera of the eye.Ultrasonics · 2021Article
- Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties.Physics in medicine and biology · 2021Article
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Authors and funding
6 authors.
Funding
Abstract
In clinical decision making, in addition to anatomical information, biomechanical properties of soft tissues may provide additional clues for disease diagnosis. Given the fact that most of diseases are originated from micron sized structures, an elastography imaging system of fine resolution (~100 µm) and deep penetration depth capable of providing both qualitative and quantitative measurements of biomechanical properties is desired. Here, we report a newly developed multi-functional ultrasonic micro-elastography imaging system in which acoustic radiation force impulse imaging (ARFI) and shear wave elasticity imaging (SWEI) are implemented. To accomplish this, the 4.5 MHz/40 MHz transducer were used as the excitation/detection source, respectively. The imaging system was tested with tissue-mimicking phantoms and an ex vivo chicken liver through 2D/3D imaging. The measured lateral/axial elastography resolution and field of view are 223.7 ± 20.1/109.8 ± 6.9 µm and 1.5 mm for ARFI, 543.6 ± 39.3/117.6 ± 8.7 µm and 2 mm for SWEI, respectively. These results demonstrate that the promising capability of this high resolution elastography imaging system for characterizing tissue biomechanical properties at microscale level and its translational potential into clinical practice.
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