Neuronal Chloride Regulation via KCC2 Is Modulated through a GABA

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

33 citing papers in PubMed, 60 citations in OpenAlex.

1. Neural regulation of cancer: from synaptic integration to neuro-immune regulation.Cellular oncology (Dordrecht, Netherlands) · 2026
   Review
2. In vivo dynamic tracking of cerebral chloride regulation using molecularly tailored liquid/liquid interfacial ultramicro iontronics.Science advances · 2024
   Article
3. Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model.Cell reports. Medicine · 2024
   Article
4. All-optical reporting of inhibitory receptor driving force in the nervous system.Nature communications · 2024
   Article
5. Impact of aging on the GABAbioRxiv : the preprint server for biology · 2024
   Article
6. Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles.EMBO reports · 2024
   Article
7. Therapeutic potential for KCC2-targeted neurological diseases.The Japanese dental science review · 2023
   Review
8. KCC2 reverse mode helps to clear postsynaptically released potassium at glutamatergic synapses.Cell reports · 2023
   Article
9. Neurodevelopment and early pharmacological interventions in Fragile X Syndrome.Frontiers in neuroscience · 2023
   Review
10. Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer's Disease.Brain sciences · 2022
    Review
11. Keeping the Balance: GABABrain sciences · 2022
    Review
12. Gephyrin Interacts with the K-Cl Cotransporter KCC2 to Regulate Its Surface Expression and Function in Cortical Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
13. Chloride imbalance in Fragile X syndrome.Frontiers in neuroscience · 2022
    Article
14. Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons.Frontiers in molecular neuroscience · 2022
    Article
15. Mechanisms and Regulation of Neuronal GABACurrent topics in behavioral neurosciences · 2022
    Review
16. Role of the cation-chloride-cotransporters in the circadian system.Asian journal of pharmaceutical sciences · 2021
    Review
17. Reviewing Evidence for the Relationship of EEG Abnormalities and RTT Phenotype Paralleled by Insights from Animal Studies.International journal of molecular sciences · 2021
    Review
18. LIFU Alleviates Neuropathic Pain by Improving the KCCNeural plasticity · 2021
    Article
19. Chloride dynamics alter the input-output properties of neurons.PLoS computational biology · 2020
    Article
20. Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes.Frontiers in molecular neuroscience · 2020
    Article

Corrections and comments

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Authors and funding

8 authors at 3 institutions in 3 countries.

Funding

Abstract

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