Evidence map›Paper›PMID 28450533›Full record

ArticleRNA (New York, N.Y.)2017

MCTBI: a web server for predicting metal ion effects in RNA structures.

Li-Zhen Sun, Jing-Xiang Zhang, Shi-Jie Chen

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. A cooperative effect of ligands, MgThe Journal of biological chemistry · 2026
    Article
  2. Driving forces of RNA condensation revealed through coarse-grained modeling with explicit MgProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
  4. Computational modeling of cotranscriptional RNA folding.Computational and structural biotechnology journal · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. RNA-ligand molecular docking: advances and challenges.Wiley interdisciplinary reviews. Computational molecular science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Li-Zhen SunDepartment of Physics, Department of Biochemistry, and Informatics Institute, University of Missouri, Columbia, Missouri 65211, USA.
Jing-Xiang ZhangSchool of Science and Technology, Zhejiang International Studies University, Hangzhou 310012, China.
Shi-Jie ChenDepartment of Physics, Department of Biochemistry, and Informatics Institute, University of Missouri, Columbia, Missouri 65211, USA.
University of Missouri · USZhejiang International Studies University · CNZhejiang University of Technology · CN

Funding

Statistical Mechanics of RNA FoldingR01GM063732 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHI-JIE · 2003 to 2018
$3.2M
New computational tools for predicting ion effects in RNA structuresR01GM117059 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHI-JIE · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM063732NIGMS NIH HHS R01 GM117059
6 · The paper itself

Abstract

Metal ions play critical roles in RNA structure and function. However, web servers and software packages for predicting ion effects in RNA structures are notably scarce. Furthermore, the existing web servers and software packages mainly neglect ion correlation and fluctuation effects, which are potentially important for RNAs. We here report a new web server, the MCTBI server (http://rna.physics.missouri.edu/MCTBI), for the prediction of ion effects for RNA structures. This server is based on the recently developed MCTBI, a model that can account for ion correlation and fluctuation effects for nucleic acid structures and can provide improved predictions for the effects of metal ions, especially for multivalent ions such as Mg

Indexed as

SoftwareHumansMetalsModels, ChemicalNucleic Acid ConformationRNAMetalsRNAfolding thermodynamicsion correlation effection effectsMonte Carlo samplingRNA folding

Identifiers

PMID28450533
PMCPMC5513060
OpenAlexW2607801096

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.