Evidence map›Paper›PMID 28450461›Full record

ArticleGenetics2017

Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.

Tai-Di Chen, Maxime Rotival, Ling-Yin Chiu, Marta Bagnati, Jeong-Hun Ko, Prashant K Srivastava, Enrico Petretto, Charles D Pusey, Ping-Chin Lai, Timothy J Aitman and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular mechanisms and therapeutic effects of different vitamins and minerals in COVID-19 patients.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

Tai-Di ChenCentre for Complement and Inflammation Research, Imperial College London, London W12 0NN, United Kingdom.
Maxime RotivalInstitut Pasteur, Unit of Human Evolutionary Genetics, Paris 75015, France.
Ling-Yin ChiuKidney Institute, Department of Nephrology, Chang Gung Memorial Hospital, 10591 Taipei, Taiwan.
Marta BagnatiCentre for Complement and Inflammation Research, Imperial College London, London W12 0NN, United Kingdom.
Jeong-Hun KoCentre for Complement and Inflammation Research, Imperial College London, London W12 0NN, United Kingdom.
Prashant K SrivastavaDivision of Brain Sciences, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, United Kingdom.
Enrico PetrettoDuke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore.
Charles D PuseyRenal and Vascular Inflammation Section, Imperial College London, London W12 0NN, United Kingdom.
Ping-Chin LaiKidney Institute, Department of Nephrology, Chang Gung Memorial Hospital, 10591 Taipei, Taiwan.
Timothy J AitmanInstitute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom.
H Terence CookCentre for Complement and Inflammation Research, Imperial College London, London W12 0NN, United Kingdom.
Jacques BehmoarasCentre for Complement and Inflammation Research, Imperial College London, London W12 0NN, United Kingdom jacques.behmoaras@imperial.ac.uk.
Imperial College London · GBCentre for Inflammation Research · GBChang Gung Memorial Hospital · TWDuke-NUS Medical School · SGInstitut Pasteur · FRUniversity of Edinburgh · GB

Funding

Medical Research Council MC_U120061454Medical Research Council MC_U120097112Medical Research Council MR/M004716/1Medical Research Council MR/N01121X/1
6 · The paper itself

Abstract

Crescentic glomerulonephritis (Crgn) is a complex disorder where macrophage activity and infiltration are significant effector causes. In previous linkage studies using the uniquely susceptible Wistar Kyoto (WKY) rat strain, we have identified multiple crescentic glomerulonephritis QTL (

Indexed as

Genetic Predisposition to DiseaseAnimalsCeruloplasminChromosome MappingGene Expression RegulationGenetic LinkageGlomerulonephritisHumansMacrophagesRatsRats, Inbred WKYCeruloplasmineQTLfine mappingGenetics of Immunityglomerulonephritismacrophagespositional cloningQTL

Identifiers

PMID28450461
PMCPMC5499168
OpenAlexW2607576351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.