Evidence map›Paper›PMID 28450457›Full record

ArticleGenetics2017

Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in

Prabha Nagarajan, Christopher T Prevost, Alexis Stein, Rachel Kasimer, Lidza Kalifa, Elaine A Sia

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prabha NagarajanDepartment of Biology, University of Rochester, New York 14627.
Christopher T PrevostDepartment of Biology, University of Rochester, New York 14627.
Alexis SteinDepartment of Biology, University of Rochester, New York 14627.
Rachel KasimerDepartment of Biology, University of Rochester, New York 14627.
Lidza KalifaDepartment of Biology, University of Rochester, New York 14627.
Elaine A SiaDepartment of Biology, University of Rochester, New York 14627 elaine.sia@rochester.edu.ORCID 0000-0002-9934-5468
University of Rochester · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The structure-specific nuclease, Rad27p/FEN1, plays a crucial role in DNA repair and replication mechanisms in the nucleus. Genetic assays using the

Indexed as

DNA Breaks, Double-StrandedDNA-Binding ProteinsDNA, MitochondrialDNA RepairFlap EndonucleasesMutagenesisMutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA-Binding ProteinsDNA, MitochondrialFlap EndonucleasesRAD27 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsDNA repairdouble-strand breakmitochondriamtDNA

Identifiers

PMID28450457
PMCPMC5499190
OpenAlexW2609323011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.