Evidence map›Paper›PMID 28450432›Full record

Trial reportAJNR. American journal of neuroradiology2017

Safety and Efficacy of Aneurysm Treatment with the WEB: Results of the WEBCAST 2 Study.

L Pierot, I Gubucz, J H Buhk, M Holtmannspötter, D Herbreteau, L Stockx, L Spelle, J Berkefeld, A-C Januel, A Molyneux and 4 more

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. The safety and effectiveness of the Contour Neurovascular System for the treatment of wide-necked aneurysms: A systematic review and meta-analysis of early experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Endoluminal flow diverters in the treatment of sidewall and bifurcation aneurysm: A systematic review and meta-analysis of complications and angiographic outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. The RISE trial: A Randomized Trial on Intra-Saccular Endobridge devices.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Trial
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

L PierotFrom the Department of Neuroradiology (L.P.), Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France lpierot@gmail.com.ORCID http://orcid.org/0000-0002-2523-4909
I GubuczNational Institute of Clinical Neurosciences (I.G., I.S.), Budapest, Hungary.ORCID http://orcid.org/0000-0002-9968-0960
J H BuhkDepartment of Neuroradiology (J.H.B., J.F.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0002-8003-6446
M HoltmannspötterRigshospitalet (M.H.), Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2536-5244
D HerbreteauCentre Hospitalier Universitaire Tours (D.H.), Tours, France.ORCID http://orcid.org/0000-0002-4533-4296
L StockxZiekenhuis Oost-Limburg Genk (L. Stockx), Genk, Belgium.ORCID http://orcid.org/0000-0002-2779-8919
L SpelleHôpital Bicêtre (L. Spelle), Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France.ORCID http://orcid.org/0000-0002-6748-8528
J BerkefeldInstitut für Neuroradiologie (J.B.), Klinikum der Johann Wolfgang Goethe-Universitaet, Frankfurt, Germany.ORCID http://orcid.org/0000-0002-3157-2453
A-C JanuelCentre Hospitalier Universitaire Toulouse (A.-C.J.), Toulouse, France.ORCID http://orcid.org/0000-0003-4910-6386
A MolyneuxOxford Neurovascular and Neuroradiology Research Unit (J.V.B., A.M.), John Radcliffe Hospital, Oxford, UK.ORCID http://orcid.org/0000-0002-8757-9021
J V ByrneOxford Neurovascular and Neuroradiology Research Unit (J.V.B., A.M.), John Radcliffe Hospital, Oxford, UK.ORCID http://orcid.org/0000-0002-1268-3000
J FiehlerDepartment of Neuroradiology (J.H.B., J.F.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-8533-7478
I SzikoraNational Institute of Clinical Neurosciences (I.G., I.S.), Budapest, Hungary.ORCID http://orcid.org/0000-0003-3730-3278
X BarreauCentre Hospitalier Universitaire Bordeaux (X.B.), Bordeaux, France.ORCID http://orcid.org/0000-0002-4932-1484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeFlow disruption with the Woven EndoBridge (WEB) device is an innovative technique for the endovascular treatment of wide-neck bifurcation aneurysms. The initial version of the device (WEB Double-Layer) was evaluated in the WEB Clinical Assessment of IntraSaccular Aneurysm Therapy (WEBCAST) study, whereas the French Observatory study evaluated both WEB Double-Layer and Single-Layer versions of the device. WEBCAST 2 was designed to evaluate the WEB Single-Layer with Enhanced Visualization. MATERIALS AND

methodsPatients with wide-neck bifurcation aneurysms for which WEB treatment was possible were included. Clinical data including adverse events and clinical status at 1 month and 1 year were collected and analyzed. A core laboratory evaluated anatomic results at 1 year following the procedure.

resultsTen European neurointerventional centers included 55 patients (38 women; 27-77 years of age; mean, 54.4 ± 10.0 years) with 55 aneurysms. Aneurysm locations were the middle cerebral artery in 25 aneurysms (45.5%), the anterior communicating artery in 16 (29.1%), the basilar artery in 9 (16.4%), and the internal carotid artery terminus in 5 (9.1%). Procedural morbidity and mortality at 1 month were, respectively, 1.8% (1/55 patients) and 0.0% (0/55 patients). Morbidity and mortality at 1 year were, respectively, 3.9% (2/51 patients) and 2.0% (1/51 patients). At 1 year, complete occlusion was observed in 27/50 aneurysms (54.0%); neck remnant, in 13/50 (26.0%); and aneurysm remnant, in 10/50 (20.0%) (adequate occlusion in 40/50, 80.0%).

conclusionsWEBCAST 2 confirms the high safety and efficacy of WEB aneurysm treatment demonstrated in the WEBCAST and French Observatory studies.

Indexed as

AdultAgedEndovascular ProceduresFemaleHumansIntracranial AneurysmMaleMiddle AgedTreatment Outcome

Identifiers

PMID28450432
PMCPMC7960101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.