Evidence map›Paper›PMID 28450390›Full record

GuidelineGut2017

British Society of Gastroenterology position statement on serrated polyps in the colon and rectum.

James E East, Wendy S Atkin, Adrian C Bateman, Susan K Clark, Sunil Dolwani, Shara N Ket, Simon J Leedham, Perminder S Phull, Matt D Rutter, Neil A Shepherd and 2 more

Registry-linked trialOpen access · bronzeAbstract readPractice GuidelineReview
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Gut, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04906343 (Endoscopic Surveillance in Patients With Serrated Polyposis Syndrome and Low-risk of Advanced Neoplasia.), which is not on this map. Cited by 138 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 4 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04906343 nacompletednot on this mapstarted 2021, after this paper: background citation

Endoscopic Surveillance in Patients With Serrated Polyposis Syndrome and Low-risk of Advanced Neoplasia.

TypeinterventionalSponsorHospital Universitario de MóstolesRan2021 to 2024Enrolled144ConditionsColonic Polyp, Colonic Neoplasms, Colonic Cancer, Serrated PolyposisArmsColonoscopy
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 4 syntheses or guidelines pooled it, 319 citations in OpenAlex.

  1. A Systematic Review onInternational journal of molecular sciences · 2021
    Pooled it
  2. Guideline
  3. Guideline
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Endoscopic Assessment and Management of Colorectal Serrated Lesions: Current Comparative Practice, Challenges, and Future Directions.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Review
  18. Article
  19. Article
  20. Review

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

James E EastTranslational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Wendy S AtkinDepartment of Surgery and Cancer, Imperial College London, London, UK.
Adrian C BatemanDepartment of Cellular Pathology, Southampton General Hospital, Southampton, UK.
Susan K ClarkThe Polyposis Registry, St. Mark's Hospital, London, UK.
Sunil DolwaniCancer Screening, Prevention and Early Diagnosis Group, Division of Population Medicine, Cardiff University, Cardiff, UK.
Shara N KetTranslational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Simon J LeedhamGastrointestinal Stem-cell Biology Laboratory, Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Perminder S PhullDepartment of Digestive Disorders, Aberdeen Royal Infirmary, Aberdeen, UK.
Matt D RutterDepartment of Gastroenterology, University Hospital of North Tees, Stockton-on-Tees, Cleveland, UK.
Neil A ShepherdGloucestershire Cellular Pathology Laboratory, Cheltenham General Hospital, Cheltenham, UK.
Ian TomlinsonOxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Colin J ReesSchool of Medicine, Durham University, Durham, UK.
University of Oxford · GBDurham University · GBAberdeen Royal Infirmary · GBCardiff University · GBCentre for Human Genetics · GBCheltenham General Hospital · GBImperial College London · GBSouthampton General Hospital · GBSt Mark's Hospital · GB

Funding

Cancer Research UK 16459Cancer Research UK 16894
6 · The paper itself

Abstract

Serrated polyps have been recognised in the last decade as important premalignant lesions accounting for between 15% and 30% of colorectal cancers. There is therefore a clinical need for guidance on how to manage these lesions; however, the evidence base is limited. A working group was commission by the British Society of Gastroenterology (BSG) Endoscopy section to review the available evidence and develop a position statement to provide clinical guidance until the evidence becomes available to support a formal guideline. The scope of the position statement was wide-ranging and included: evidence that serrated lesions have premalignant potential; detection and resection of serrated lesions; surveillance strategies after detection of serrated lesions; special situations-serrated polyposis syndrome (including surgery) and serrated lesions in colitis; education, audit and benchmarks and research questions. Statements on these issues were proposed where the evidence was deemed sufficient, and re-evaluated modified via a Delphi process until >80% agreement was reached. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) tool was used to assess the strength of evidence and strength of recommendation for finalised statements.

Indexed as

AdenomaAdenomatous Polyposis ColiBenchmarkingBiomarkersCell Transformation, NeoplasticColitisColonic PolypsColonoscopyCpG IslandsDNADNA MethylationFecesHumansParasympatholyticsPolypsPrecancerous ConditionsBiomarkersDNAParasympatholyticsCOLONIC NEOPLASMSCOLONOSCOPYCOLORECTAL CANCERHISTOPATHOLOGYPOLYPOSIS

Identifiers

PMID28450390
PMCPMC5530473
OpenAlexW2608438922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.